objective(s):biochemical markers are important for the timely diagnosis and follow-up of ischemic events. most of the markers have been previously studied in the context of cardiac ischemia. however, research on markers of non-cardiac events has been insufficient. therefore, we investigated the relationship between troponin and myoglobin which are commonly used markers of cardiac ischemia, in n...

BACKGROUND Evidence is accumulating in favour of a link between erectile dysfunction (ED) and coronary artery diseases. We investigated the presence of cardiac injury in patients who have had arteriogenic and nonarteriogenic ED using the hs-Tn levels. METHODS The diagnosis of ED was based on the International Index of Erectile Function 5-questionnaire (IIF-5) and patients were classified as a...

of evidence The High Sensitivity Cardiac Troponin T Assay for Rapid Rule-out of Acute Myocardial Infarction trial was a prospective, multicentre, diagnostic study done at 12 sites, across three continents to validate the diagnostic accuracy of the troponin T 0-hour/1-hour algorithm for rule-in and rule-out of acute myocardial infarction. Current troponin assays for the diagnosis of myocardial i...

To meet the criteria defined in the universal definition of acute myocardial infarction (AMI), sensitive assays for cardiac troponins I and T have recently been introduced into clinical medicine. Such assays are commonly understood to have a detection limit ,99th percentile of a reference population and a total imprecision at the 99th percentile ≤10%. The analytical performance of these assays,...

Abstract Background High-sensitivity (hs) assays for the measurement of cardiac troponin T (cTnT) and I (cTnI) are now used widely diagnosis myocardial infarction. However, it is also increasingly apparent that concentrations well below thresholds in acute coronary syndromes may provide diagnostic prognostic information patients with chronic (CCS). Purpose This study aimed at evaluating associa...