The continuing efforts of investigators to achieve the best physical and clinical performances from PET (positron emission tomography) and related hybrid cameras (PET/CT and PET/MRI) have led to remarkable technical advances in hardware and software. Time of flight (TOF) information measurement, which has been enabled thanks to the invention of fast, heavy crystals and advances in fast light de...

OBJECTIVE Nuclear medicine is becoming increasingly important in the early detection of malignancy. The advantage of nuclear medicine over other imaging modalities is the high sensitivity of the gamma camera. Nuclear medicine counting equipment has the capability of detecting levels of radioactivity which exceed background levels by as little as 2.4 to 1. This translates to only a few hundred c...

  Combined PET/CT scanners now play a major role in medicine for in vivo imaging in oncology, cardiology, neurology, and psychiatry. As the performance of a scanner depends not only on the scintillating material but also on the scanner design, with regards to the advent of newer scanners, there is a need to optimize acquisition protocols as well as to compare scanner ...

Developments in positron emission tomography (PET) technology have resulted in systems with finer detector elements designed to further improve spatial resolution. However, there is a limit to what extent reducing detector element size will improve spatial resolution in PET. The spatial resolution of PET imaging is limited by several other factors, such as annihilation photon non-collinearity, ...

FDG-PET imaging of primary breast cancer tumors is currently not a generally accepted indication. This is explained by scientific research in the early days of PET imaging, that demonstrated poor visibility of tumors with FDG within surrounding glandular tissue, and poor anatomical localization of lesions within a breast on PET alone. On the other hand, MRI is now developing as a standard tool ...

UNLABELLED Differential diagnosis of pancreatic lesions still remains a problem. Whereas CT provides high spatial resolution, PET detects malignant lesions with high sensitivity. The objective of this study was to evaluate the clinical benefit of PET/CT image fusion in the diagnostic workup of pancreatic cancer. METHODS One hundred four patients with suspected pancreatic lesion underwent trip...

This paper studied PET intrinsic spatial resolution and contrast recovery improvement for PET/MRI dual modality systems. A Monte Carlo simulation tool was developed to study positron diffusion in tissues with and without a magnetic field for six commonly used isotopes ((18)F, (11)C, (13)N, (15)O, (68)Ga and (82)Rb). A convolution process was implemented to investigate PET intrinsic spatial reso...

Recently, positron emission tomography (PET) is playing an increasingly important role in the diagnosis and staging of cancer. Combined PET and X-ray computed tomography (PET-CT) scanners are now the modality of choice in cancer treatment planning. More recently, the combination of PET and magnetic resonance imaging (MRI) is being explored in many sites. Combining PET and MRI has presented many...

OBJECTIVE To assess the diagnostic value of whole-body positron emission tomography (PET), computed tomography (CT), magnetic resonance imaging (MRI), and the fusion of PET and CT (PET/CT) and PET and MRI (PET/MRI) in the detection of metastatic disease of gastrointestinal carcinoid tumors. MATERIALS AND METHODS This prospective study included six patients with extensive nonresectable metasta...

737 Open Access-This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the source is credited. Sir–With great interest we read the paper of Ullmark et al. on using positron emission tomography (PET) to assess bone metabolic activity (Ullmark et al. 2009). PE...