OBJECTIVE To compare the effectiveness of high-frequency oscillatory ventilation with conventional mechanical ventilation in pediatric patients with respiratory failure. SETTING Five tertiary care pediatric intensive care units. DESIGN A prospective, randomized, clinical study with crossover. PATIENTS Seventy patients with either diffuse alveolar disease and/or airleak syndrome were rando...

Management of acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS) is largely supportive, with the use of mechanical ventilation being a central feature. Recent advances in the understanding of ALI/ARDS and mechanical ventilation have revealed that lung-protective ventilation strategies may attenuate ventilator-associated lung injury and improve patient morbidity/mortality...

purpose: hypercapnia increases minute ventilation (v’e) with little effect on heart rate (hr), whereas hypoxia may increase hr without affecting v’e. however, the effects of hypercapnia and hypoxia on both heart rate variability (hrv) and the clustering of heart beats during spontaneous breathing (respiratory sinus arrhythmia – rsa), are not clear. methods: in this study, 10 human volunteers br...

High-frequency oscillatory ventilation (HFOV) is novel type of artificial lung ventilation characterized by low tidal volume and high ventilatory frequency compared with conventional mechanical ventilation. Obstruction diseases like asthma or chronic obstruction pulmonary disease are supposed to be contraindications for HFOV. Mechanical properties of the patient circuit and its parts are studie...

Manual jet ventilation (20 b.p.m.) and high frequency jet ventilation (300 b.p.m.) were compared during laser resection of tracheo-bronchial stenosis under general anaesthesia. Both methods provided similar blood-gas tensions at the 10th min of surgery in patients with tracheal stenosis. In patients with bronchial stenosis high frequency jet ventilation resulted in modest hypercarbia and manual...