The crystal structure of the title compound, C(11)H(18)N(+)·Br(-), has been determined as part of an ongoing study of the influence of the alkyl chain length on amphiphilic activity of quaternary ammonium salts. The title salt forms a three-dimensional network of ionic contacts through weak C-H⋯Br hydrogen bonds, with donor-acceptor distances in the range 3.757 (2)-3.959 (2) Å, in which methyl ...

Therapy with bronchodilators forms the pharmacologic foundation of the treatment of patients with COPD. Bronchodilators can significantly lessen dyspnea, increase airflow, improve quality of life, and enhance exercise performance. While bronchodilators decrease airway resistance and lessen dynamic hyperinflation in patients with COPD, they have not been shown to alter the rate of decline in FEV...

Condensation and cyclization of 5-hydroxy- 1,2,4- thiadiazol-2-yl hydrazine 1 with pyruvic acid, phenacyl bromide, propargyl bromide and ally1 bromide afforded compounds 2,5,7 3, 4 ,6 and 8 respectively, Reaction of 1 with epichforohydrine afforded 4-hydroxy-N-[5-hydroxy- 1 ,3,4-thiadiazoly1] pyrazolidine 9

Cationic and zwitterionic boryl bromide species and a borenium-boryl bromide cation have been synthesised which represent new N-donor stabilised cationic boron compounds with β-diketiminate ligands. The unexpected borenium-boryl bromide results from a head-to-tail dimerisation of the corresponding zwitterionic boryl bromide accompanied by proton migration. The electronic nature of these new spe...

a highly selective electrode for bromide ion based on aza pyrilium derivative as an excellentionophore is described.the sensor exhibits a good linear response with a slope of ( 60±1 ) mv per decadeover the concentration range of ( 1×10-3 – 9×10-6 m ) , and a detection limit of ( 3×10-6 m ) of bromideions .the electrode response is independent of ph in the range of(4.0 –9.5).selectivity coeffici...

BACKGROUND Inhaled anticholinergics and beta agonists are widely used in the treatment of patients with chronic obstructive pulmonary disease (COPD). However, dosage requirements have not been thoroughly evaluated and comparative dose-response data for these agents are limited. METHODS Twenty men with stable COPD of mean (SD) age 69.4 (5.8) years and FEV1 0.93 (0.38) litres were studied in ra...