Supercooled liquids near the glass transition exhibit the phenomenon of heterogeneous relaxation; at any specific time, a nominally homogeneous equilibrium fluid undergoes dynamic fluctuations in its structure on a molecular distance scale with rates that are very different in different regions of the sample. Several theoretical and simulation studies have suggested a change in the nature of th...

NUCLEAR RIBONUCLEAR PROTEINS hnRNP L, hnRNP A1 and hnRNP M Kenneth J. Dery , Shikha Gaur , Marieta Gencheva, Yun Yen, John E. Shively and Rajesh K. Gaur Division of Immunology, Clinical and Molecular Pharmacology Beckman Research Institute of the City of Hope 1450 E. Duarte Road, Duarte, CA 91010 These authors contributed equally to the research Running title: Alternative splicing of CEACAM1 pr...

BACKGROUND Central to the design of a randomised controlled trial is the calculation of the number of participants needed. This is typically achieved by specifying a target difference and calculating the corresponding sample size, which provides reassurance that the trial will have the required statistical power (at the planned statistical significance level) to identify whether a difference of...

A sample size calculation for logistic regression involves complicated formulae. This paper suggests use of sample size formulae for comparing means or for comparing proportions in order to calculate the required sample size for a simple logistic regression model. One can then adjust the required sample size for a multiple logistic regression model by a variance inflation factor. This method re...

Exact power and sample size calculation for bioequivalence studies with high order crossover designs using statistical software nQuery are presented. Such calculation can be very easily performed, and thus provides a convenient tool for practical usage.

In clinical research, parameters required for sample size calculation are usually unknown. A typical approach is to use estimates from some pilot studies as the true parameters in the calculation. This approach, however, does not take into consideration sampling error. Thus, the resulting sample size could be misleading if the sampling error is substantial. As an alternative, we suggest a Bayes...

BACKGROUND Recent studies have shown that heterogeneous nuclear ribonucleoprotein U (hnRNP U), a component of the hnRNP complex, contributes to stabilize the kinetochore-microtubule interaction during mitosis. CENP-W was identified as an inner centromere component that plays crucial roles in the formation of a functional kinetochore complex. RESULTS We report that hnRNP U interacts with CENP-...

Background: The purpose of this study is to fabricate inexpensive in-house low cost homogeneous and heterogeneous human equivalent thorax phantom and assess the dose accuracy of the Treatment Planning Systems (TPS) calculated values for different lung treatment dosimetery. It is compared with Thermoluminescent Dosimeter (TLD) measurement. Materials and Methods: Homogeneous and heterogeneous tho...

PURPOSE Heterogeneous ribonucleoprotein K (hnRNP K) regulates thymidine phosphorylase (TP) mRNA stability. The aim of the present study was to analyze hnRNP K and TP expression in nasopharyngeal carcinoma (NPC) and to evaluate the prognostic and therapeutic potential of these two markers. EXPERIMENTAL DESIGN We analyzed hnRNP K and TP expression immunohistochemically in 121 clinically proven ...

Semantic Manufacturing has grown as an application area of the Semantic Web Framework. This approach enables reasoning on products in the form of ontologies and involves products requirements verification within its scope. However, there are cases where the expressivity of OWL, a defacto standard for the Semantic Web, is insufficient for expressing fundamental features of designs. As such featu...