BACKGROUND The majority of previous heroin cue-reactivity functional magnetic resonance imaging (fMRI) studies focused on local function impairments, such as inhibitory control, decision-making and stress regulation. Our previous studies have demonstrated that these brain circuits also presented dysfunctional connectivity during the resting state. Yet few studies considered the relevance of res...

Socio-demographic variables of 189 out-patients with drug abuse who were registered at the Hospital for Psychiatric Diseases, Srinagar were studied. Most of the drug abusers were male, the majority (57.2%) being in the 26-35 age group. Cannabis was the commonest substance abused, followed by heroin. Cannabis abusers had the longest duration of drug use but the lowest rate of drug dependence (29...

BACKGROUND Several types of medications have been used for stabilizing heroin users: Methadone, Buprenorphine and levo-alpha-acetyl-methadol (LAAM.) The present review focuses on the prescription of heroin to heroin-dependent individuals. OBJECTIVES To compare heroin maintenance to methadone or other substitution treatments for opioid dependence regarding: efficacy and acceptability, retainin...

years. however, the nature and initial factors associated with this serious health problem have not been studied yet. methods: to understand this issue, a cross-sectional study was conducted and sixty treatment and nontreatment seekers who met the diagnostic and statistical manual of mental disorders, 4th ed., text revision (dsm.iv-tr) criteria for drug dependence with mean age of 28.7 (± 8.3) ...

BACKGROUND Co-use of heroin kerack with methamphetamine (MA) is a new epidemic health concern among Iranian female drug users. Yet, little is known about this issue because of stigma. OBJECTIVES The current study aimed to investigate the reasons associated with initial and continued co-use of heroin kerack with MA among two groups of regular and recreational female co-users, their motivations...

BACKGROUND Addiction to opioids, or opioid dependence, encompasses the biopsychosocial dysfunction seen in illicit heroin injectors, as well as aberrant behaviours in patients prescribed opioids for chronic nonmalignant pain. OBJECTIVE To outline the management of opioid dependence using opioid pharmacotherapy as part of a comprehensive chronic illness management strategy. DISCUSSION The sa...

Drug and alcohol dependence are associated with enhanced attention for drug-related stimuli. This cognitive processing bias has been suggested to be related to craving and to represent one of the core mechanisms of addition. The present study tests the hypothesis that enhanced attention for heroin cues is mediated by the dopaminergic system using haloperidol as dopamine antagonist. In a double ...

BACKGROUND AND AIMS Smartphone addiction, its association with smartphone use, and its predictors have not yet been studied in a European sample. This study investigated indicators of smartphone use, smartphone addiction, and their associations with demographic and health behaviour-related variables in young people. METHODS A convenience sample of 1,519 students from 127 Swiss vocational scho...

AIMS The aim of this study was to compare patterns of drug use and dependence between homosexually experienced and exclusively heterosexually experienced individuals. DESIGN We used a cross-sectional national household interview survey conducted in the United States. SETTING Secondary data analysis of the 1996 National Household Survey on Drug Abuse was employed. PARTICIPANTS Participants...