A 46-year-old woman with moderate lens subluxation and Marfan ́s syndrome underwent a phacoemulsification on the right eye with a sutureless Henderson Capsular Tension Ring (HCTR) implantation. The surgical procedure and the postoperative follow up period were uneventful, with a best corrected visual acuity (BCVA) of 0 (LogMAR). Seven months after surgery the patient presented an inferomedial di...

Purpose. To compare the feasibility of cataract surgery with implantation of endocapsular supporting devices and intraocular lens (IOL) in subluxated cataract in phacoemulsification and manual small incision cataract surgery (MSICS). Design. Prospective randomized intervention case series consisting of 60 eyes with visually significant subluxated cataract. Method. The patients were randomly dis...

PURPOSE Cataract is a clinically and genetically heterogeneous disorder of the ocular lens and an important cause of visual impairment. The aim of this study was to map and identify the gene underlying autosomal dominant cataract segregating in a four-generation family, determine the lens expression profile of the identified gene, and test for its association with age-related cataract in a case...

BACKGROUND AlphaA-crystallin (CRYAA/HSPB4), a major component of all vertebrate eye lenses, is a small heat shock protein responsible for maintaining lens transparency. The R49C mutation in the alphaA-crystallin protein is linked with non-syndromic, hereditary human cataracts in a four-generation Caucasian family. METHODS This study describes a mouse cataract model generated by insertion of a...

Congenital cataracts are rare and occur in developed countries with a frequency of 30 cases among 100,000 births with a further 10 cases being diagnosed during childhood. They reflect mainly genetically caused developmental alterations in the lens and surrounding ocular tissues. Even if modern Human Genetics has made large steps forward in the characterization of human hereditary disorders, the...

Cataracts are opacities within the lens that may affect a small portion of the lens or the entire lens. Cataracts are a leading cause of blindness in dogs. They may be due to hereditary factors, metabolic diseases, inflammation, or other causes. A thorough ophthalmic and physical examination, complete blood cell count, biochemical evaluation, electroretinography, and ocular ultrasonography shou...

conclusions the treatment of symptomatic ecu instability is still controversial, especially for acute dislocations. depending on the type of injury many surgical techniques have been proposed. combination of direct repair of the tendon’s subsheath and reinforcement with an extensor retinaculum graft is a reliable option. introduction dislocation/subluxation of the extensor carpi ulnaris (ecu) t...

Neck involvement in cases of rheumatoid arthritis is extremely common, and the radiological features have been investigated by several authors, particularly Martel (1961, 1964), Bland, Davis, London, Van Buskirk, and Duarte(1963), Serre, Simon, Janicot, and Levy (1964) and Conlon, Isdale, and Rose (1966). The features most characteristic are atlanto-axial subluxation, serial subluxation, and di...

Subluxation syndrome is a legitimate, potentially testable, theoretical construct for which there is little experimental evidence. Acceptable as hypothesis, the widespread assertion of the clinical meaningfulness of this notion brings ridicule from the scientific and health care communities and confusion within the chiropractic profession. We believe that an evidence-orientation among chiroprac...