ETHNOPHARMACOLOGICAL RELEVANCE Laggera alata, as a traditional Chinese herbal medicine, has been widely used to ameliorate some ailments associated with inflammation including hepatitis in folk. AIM OF THE STUDY Based on anti-inflammatory activity of total phenolics from Laggera alata (TPLA), to further validate the remarkable curative effect Laggera alata in hepatitis, hepatoprotective effec...

Previously explored combination therapies mostly involved the use of bioactive molecules. It is believed that herbal compounds containing multiple plant products have synergistic hepatoprotective effects and could enhance the desired actions. To investigate the combination of ethanolic fruits extract of Solanum xanthocarpum (SX) and Juniperus communis (JC) against Paracetamol (PCM) and Azithrom...

The objective of the study was to investigate the methanol extract of Pavonia zeylanica (MEPZ) against acetaminophen induced hepatotoxicity and antioxidant activity in Wistar albino rats.The methanol extract of pavonia zeylanica (200, and 400 mg/kg body weight) was administered orally to two groups of rats (six animals per group) in order to evaluate the protective effect of the extract in rats...

A new digalacturonide flavone, luteolin 7-O-beta-galacturonyl-(2 --> 1)-O-beta-galacturonide (1), was isolated along with nine known flavone glycosides from the aqueous methanolic extract of Lantana camara (L.) flowers. Their structures were determined on the basis of the spectral data. The extract of L. camara was evaluated for antioxidant and hepatoprotective properties in the acetaminophen-i...

Aim of the study was to evaluate the hepatoprotective activity of ethanolic seed extract of Lawsonia inermis against paracetamol induced liver damage in rats. Wistar albino rats of either sex were divided in to 5 groups of 6 each. The rats were intoxicated with paracetamol (750mg/kg) at every 72 hrs for 21 days. Silymarin (50mg/kg) and Lawsonia inermis (200 & 400 mg/kg) were orally administered...

The aim of the study is to investigate the hepatoprotective activity of Melia azedarach L leaves extracts against simvastatin induced hepatotoxicity. The phytochemical screening was carried on the leaves extracts of Melia azedarach revealed the presence of some active ingredients such as Alkaloids, Tannins, Sponginess, Phenols, glycosides, steroids, terpenoids and flavonoids. Leaves of Melia az...

A new heptapeptide GAGPHGG (OC1) was isolated from Carapax trionycis which was a traditional Chinese medicine (TCM) used for treatment of hepatic diseases. The structure of OC1 was characterized by MS, NMR techniques, together with amino acid sequence analysis. The hepatoprotective activity of OC1 was evaluated in vivo using the CCl4-induced acute liver injury model. Combining the pathological ...