Abstract Hepatocellular Carcinoma (HCC) is one of the deadliest forms cancer. Recent years have seen significant advances for HCC treatment, but up to 70% patients remain at high risk recurrence necessitating urgent need more effective therapies. Plasmacytoid dendritic cells (pDCs) heavily infiltrate liver tumor tissues, contribute an immunosuppressive microenvironment (TEM), and promote growth...

Background: Programmed death protein-1 (PD-1) inhibitors and liver transplantation (LT) are alternative treatments for hepatocellular carcinoma (HCC) patients. The application of PD-1 HCC therapy increases T cell immune activity, while immunosuppression is required patients receiving transplantation. More clinical investigation to determine methods balance these treatment effects. In this artic...

patients and methods this was a retrospective study including 207 consecutive patients who were enrolled using computerized hepatocellular carcinoma database consisting of 105 patients who underwent combined tace with rfa, and 102 patients who underwent tace alone with long-term follow-up. results the complete remission rate was meaningfully higher in the combination group (97.1%, 102/105) than...

Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and a leading cause of cancer-related death worldwide. Despite advances in prevention techniques, screening, new technologies both diagnosis treatment, incidence mortality continue to rise. Cirrhosis remains important risk factor for development HCC regardless etiology. Chronic medical conditions such as diabetes mellitu...

Hepatocellular carcinoma (HCC) has an increasing incidence worldwide, and it is the leading cause of death in patients with cirrhosis. The criteria for the diagnosis of Hepatocellular carcinoma (HCC) have been defined at the Barcelona2000 EASL (European Association fof the Study of the Liver) conference1. Not so defined were the staging criteria, a useful tool to the physician to choose the mos...

Conventional strategies against hepatocellular carcinoma (HCC) remain unsatisfactory due to its invasiveness and poor prognosis. Herein, it is utmost imperative require alternative modalities with less invasiveness, good clinical efficacy, low side effects. A combination of photothermal therapy (PTT) photodynamic (PDT) an emerging modality refractory HCC. To date a majority PTT/PDT paradigms ha...

OBJECTIVES Histone deacetylases (HDACs) plays important roles in the regulation of genes expression and contribute to the growth of cancer cells. The present study aimed to investigate the function of HDAC5 in human hepatocellular carcinoma (HCC). PATIENTS AND METHODS The expression of HDAC5 in human hepatocellular carcinoma tissues and cells was detected. MTT assay was used to measure the pr...

The roles of Pinin have been well studied in epithelial cell-cell adhesion and RNA alternative splicing, which suggests its involvement in cancer progression. However, little is known about the association between Pinin expression and hepatocellular carcinoma (HCC) tumorigenesis. In this study we report increased expression of Pinin in HCC tissues and cells. Elevated levels of Pinin closely ass...

Hepatocellular carcinoma (HCC) is the most common malignant tumor of the liver. Hepatitis B virus infection is one of the most important etilogical factors of HCC. In this case report, a patient with HCC previously infected and having ongoing immunity against hepatitis B virus will be discussed. How to cite this article Ates I, Kaplan M, Demirci S, Altiparmak E. A Hepatocellular Carcinoma Cas...

Hepatocellular carcinoma (HCC) represents the third most common cause of cancer-related deaths worldwide and efficient treatment options are urgently needed. Based on its pathogenesis as well as a number of correlative studies, immunotherapy represents a potential therapeutic option for patients with HCC. However, tumors have also evolved numerous immune escape mechanisms, such as the generatio...