BACKGROUND The small delta antigen protein of hepatitis delta virus (HDV) has been shown to be important for replication of the virus and essential for the viral life cycle. Therefore, it may be an appropriate target for designing biological experiments for drug development to identify the potential inhibitors of hepatitis D. OBJECTIVES To identify a novel molecule as possible drug candidate ...

Introduction The overall health status of workers of tea garden of Bangladesh is below the national standard. Also, almost nothing has been reported about status of hepatitis virus infection among these population and there is also a lack of consensus. Materials and methods Several health-related facts, especially those of liver diseases, were collected from 130 workers of tea garden via ques...

results patients’ age ranged from 15 to 65 years (mean = 35.54 ± 14.85). thirty four (1.0%) of the subjects were positive for hbsag, of whom, 2.9 % (1 of 34 cases) were also positive in pcr-based screening. elisa tests for hbeag, hbeab, and hbcab igm were positive in one (2.9 %), 27 (79.4%) and one (2.9 %) cases, respectively. conclusions according to our results, hbsag was positive in 0.53 of ...

background : to analyze serologic markers of hepatitis g virus (gbv-c) infection in iranian blood donors and two major groups of multitransfused patients, hemophiliacs and thalassemics. methods :nine hundred and five serum samples collected from the volunteer blood donors and two patient groups under the study were tested for the presence of antibodies to the gbv-c antigen (anti e2 ) by an elis...

BACKGROUND Infections caused by Hepatitis B are one of the world health's most serious problems. According to assessments, nearly 500,000 to 1.2 million people die each year due to chronic hepatitis, cirrhosis of the liver and hepatocellular carcinoma. Hepatitis B is one of the diseases which can be transferred through blood and its products. Clinical importance of genotypes of hepatitis B viru...

Chronic Hepatitis B (HBV) and Hepatitis C (HCV) virus infections are global health problems which may cause cirrhosis and even hepatocellular carcinoma. Hepatitis D virus (HDV) though a satellite virus of HBV, can also cause chronic infection. Serologic and molecular tools are needed for the diagnosis, monitoring and therapeutic management of chronic viral hepatitis associated with HBV, HDV and...

Background: Scleroderma is a chronic systemic disorder that affects the connective tissues. It is characterized by several immune manifestations, inflammation, vascular damage, and fibrosis. Some of the viral infections with complex mechanisms are involved in the development and progression of many autoimmune diseases, such as scleroderma. The present study aimed to investigate the serological ...

To clarify the influence that a recently identified SEN virus (SENV) has on hepatitis C virus (HCV) response to therapy with interferon plus ribavirin, 2 SENV variants, SENV-D and SENV-H, were studied in 100 patients with chronic hepatitis C; 57 of these patients were positive for SENV-D/H DNA, and there were no differences, in clinicopathological features, between patients with and without SEN...

background: hepatitis e virus is an enterically transmitted virus that is endemic in south asia and this virus is one of the most important cause of acute hepatitis in this region. although hepatitis e virus (hev) is not a leading cause for chronic hepatitis, the role of hev in exacerbation of chronic liver disease is certain. materials and methods: 100 cirrhotic cases (50 hepatitis b and 50 he...