Dialysis-related amyloidosis (DRA) is a common complication associated with long-term haemodialysis therapy. The elimination of beta2-microglobulin (beta2m), the major constituent of the amyloid fibrils in DRA, from circulation has been expected to bring some clinical benefit. Recently, a direct haemoperfusion method using selective beta2m absorption column to eliminate circulating beta2m has b...

Plasma taken from hepatic failure dogs induced by hepatic ischemia was used to observe the variation in its chromatogram obtained by conducting a high performance gel-chromatography (TSK G2000SW used). The progress of hepatic failure caused a distinct increase in the middle molecular (MM) fractions (m. w. over 500), which showed a good correlation with the condition of progressing hepatic failu...

Charcoal haemoperfusion used to treat a 56-year-old woman who had taken a very large overdose of meprobamate was followed by fully recovery. The plasma clearance of meprobamate was 153 ml/min and this compares favourably with values obtained for haemodialysis. The indications for haemoperfusion are reviewed.

A 28-year-old unemployed bar manager presented to the Casualty Department at 4.00 am having consumed fifty 400 mg tablets of a slow-release preparation of theophylline ("Uniphylline" Napp Laboratories) three hours previously. An asthmatic since childhood, he had been taking 400 mg of this preparation daily for the previous year. There was no past psychiatric history and the taking of the overdo...

OBJECTIVE This study was aimed to analyze the scavenging effect of haemoperfusion on plasma paraquat (PQ) and to evaluate the clinical significance of PQ examination in the treatment of patients with acute paraquat poisoning. METHODS 85 patients with acute paraquat intoxication by oral ingestion were admitted in West China Hospital from Jun, 2010 to Mar, 2011. A standardized therapeutic regim...