idiopathic acquired hemolytic atsemia, Group II, hemolytic atsemia followitsg irus pmseumomsia and Group III, chrotsic hemolytic atsemia with hemoglohitsuria and Raynaud’s phemsomena. A detailed accoumst. of the climsical aspects of tise three patients of Group III was published by Ferrimams, Dacie, Keele amid Fullerton2 who also made an amsalysis of msine similar cases reported in the literatu...

By CEsAR REYNAFARJE AND JOSE RAMOS H UMAN bartonellosis, or Carrion’s disease, is characterized by rapid development of severe hemolytic anemia in the acute stage of the disease caused by infestation of the erythrocytes by Bartonella bacilliformis. The bacterium described by Barton’ in 1905 is visible in the red cells at the acute stage, so that their examination makes the diagnosis very easy (...

INTRODUCTION Unlike autoimmune hemolytic anemia (AIHA), literature on the etiological study of non-autoimmune hemolytic anemia (non-AIHA) is scarce. The incidence and prevalence of non-AIHA in different geographic regions are largely unknown perhaps owing to the lack of perspective investigation and different profiles of etiologies from different geographic regions. We aimed to examine the real...

OBJECTIVE Autoimmune hemolytic anemia is characterized by the production of autoantibodies against erythrocyte membrane antigens. This study was carried out to identify the clinical, immunological and outcome characteristics of autoimmune hemolytic anemia patients treated at the (HC-UFMG) Pediatric Hematology Unit and the Hemocentro de Belo Horizonte. METHODS We evaluated 17 patients younger ...

Blood group antigens (BGAs) can act as functional molecules but also can evoke autoantibodies and alloantibodies, causing autoimmune hemolytic anemia, hemolytic disease of the newborn and hemolytic transfusion reactions. In Section I, Dr. Marilyn Telen discusses physiologic and pathologic functions of RBC BGA-bearing molecules. She reviews some associations of BGAs with RBC membrane integrity a...

A new immunochemical method was used to quantitate the number of C3 molecules bound to human red cells in vitro or in vivo and to assess the clinical significance of cell-bound C3 in immune hemolysis. In addition, results utilizing the immunochemical method were compared with those obtained using commonly performed semiquantitative serologic techniques such as the antiglobulin test and antiglob...

BACKGROUND Atypical hemolytic uremic syndrome (aHUS) is a rare disease characterized by hemolysis, thrombocytopenia, and renal dysfunction. It is a disease related to genetic mutations in the alternative complement pathway and has a distinct pathophysiology but is difficult to differentiate from other thrombotic microangiopathies. CASE REPORT We present a case of a 59-year-old female patient ...