the purification of biomolecules is a necessary step in many biochemical researches. in this regard, developments of convenient, specific and low cost methods of purification are of particular interest. given the human hemoglobin (hb) affinity toward some charged carbohydrates, interaction of this molecule with human chorionic gonadotropin (hcg) which is a glycoprotein hormone containing sialic...

patients and methods five hundred and sixteen serum samples of the patients undergoing hemodialysis and kidney transplantation from various cities of khuzestan province were collected. anti-hepatitis g e2 antibodies were investigated by elisa method. rnas were extracted from serums and hepatitis g rna was detected by rt-pcr. results of the 516 samples, 38 (7.36%) specimens were positive for ant...

background: thalassemia is the most common single-gene disorder that carries along many difficulties and effects such as oral and dental problems in patients. this study aimed to determine dmft indicator and its correlation with the amount of serum ferritin and hemoglobin in patients with thalassemia major. materials and methods: this cross-sectional study has been conducted by descriptive-anal...

results according to the results there is a significant statistical difference between average numbers of models before and after educational intervention (p < 0.001). also hba1c and fbs after educational intervention were lower (p < 0001). conclusions applying the hbm model proved is very effective in developing an educational program for diabetics, to control their blood sugar. besides such p...

With the increasing demand for blood transfusions, production of human hemoglobin (Hb) from sustainable sources is increasingly studied. Microbial an attractive option, as it may provide a cheap, safe, and reliable source this protein. To increase by yeast Saccharomyces cerevisiae, degradation Hb was reduced through several approaches. The deletion genes HMX1 (encoding heme oxygenase), VPS10 re...

BACKGROUND Single nucleotide mutations in alpha1 or alpha2 genes produce abnormal alpha-chain hemoglobins. Hemoglobin Q disorders including hemoglobin Q-Iran, hemoglobin Q-Thailand, and hemoglobin Q-India are important hemoglobin variants. Herein, we report on the presence and hematologic and molecular features of hemoglobin Q-Iran [alpha75 (EF4) Asp-->His] in 20 members of 11 families includin...