background & objectives: in the 6-billion-population world 2000, approximately 10 million cancers were diagnosed, among which there were an estimated 6.2 million cancer deaths. whereas the universality of cancer incidence and mortality is established, the burden of cancer by type or organ site is distributed unequally between developing and industrialized nations. we want to collect some inform...

Hematopoiesis is the process of blood cell production, which involves the maintenance and proliferation of hematopoietic progenitor cells and their differentiation into mature, functional erythrocytes, leukocytes, and platelets. Normal hematopoiesis depends on the presence of (1) normal pluripotent hematopoietic stem cells, which are capable of maintaining differentiated hematopoietic cell prod...

Aim . To reveal the significance of major histocompatibility complex and human leukocyte antigen evolutionary divergence in transplantation allogeneic hematopoietic stem cells. The article traces evolution discusses reasons for its formation on example recognition system invertebrates, plants, jawed vertebrates humans. concepts immunopeptidome have been defined; data their impact therapy outcom...

The Drosophila lymph gland is the hematopoietic organ in which stem-like progenitors proliferate and give rise to myeloid-type blood cells. Mechanisms involved in Drosophila hematopoiesis are well established and known to be conserved in the vertebrate system. Recent studies in Drosophila lymph gland have provided novel insights into how external and internal stresses integrate into blood proge...

cellular and tissue activities highly depend on environmental ph. murine lung tissue, when cultured properly in-vitro, is a potent producer of hematopoietic growth factors. we have studied the effect of ph on the production of hematopoietic growth factors and protein synthesis by the murine lung in-vitro. various concentrations of nahc03 were used to adjust the ph of the culture medium under co...

The concept and characteristics of different types of hematopoietic cells have been described. Hematopoietic stem cells are currently considered to exist in a variety of populations with different degrees of commitment towards a particular cell line. By a combination of animal studies and studies with hematopoietic disorders, the concept of dividing hematopoietic stem cells into uncommitted and...