OBJECTIVES We sought to determine joint outcomes relative to impact level of athletic participation among school-aged children who had hemophilia and were taking prophylactic factor replacement, as well as to investigate prognostic factors for joint outcomes. METHODS School-aged boys with severe hemophilia A or B at a single center were included in the study. Clinical data on baseline joint s...

The presence of an intra-articular knee effusion requires an extensive differential diagnosis and a systematic diagnostic approach. Pediatric knee effusions occur most commonly as acute hemarthroses after traumatic injury. However, the knee joint is susceptible to effusions secondary to a wide variety of atraumatic causes. Special attention is required in the atraumatic effusion to distinguish ...

A 26 year old woman presented to the accident and emergency department with a painful right elbow. There had been no history of trauma. Clinical examination suggested an effusion, which was confirmed on radiological examination. Her elbow was aspirated and revealed a haemarthrosis. Subsequent investigations revealed a diagnosis of von Willebrand's disease (vWD). A spontaneously occurring effusi...

OBJECTIVE To study the clinical characteristic, presentation, complications in patients with congenital coagulation disorders who attended the Congenital Coagulation Disorders Center, Baghdad, Iraq. METHODS This cross-sectional study was conducted in the Center of Congenital Coagulation Disorders, Al-Mansour Pediatric Teaching Hospital, Baghdad, Iraq between March 2008 and August 2008. The sa...

To prevent hemophilic arthropathy, prophylactic treatment of children with severe hemophilia should be started before joint damage has occurred. However, treatment is expensive, and the burden of regular venipunctures in young children is high. With the aim of providing information on starting prophylaxis on the basis of individual patient characteristics, the effect of postponing prophylaxis o...

S PONTANEOUS BLEEDING episodes and hemorrhage following surgery or trauma in hemophilia can be treated readily with the potent Factor VIII concentrates now available.1#{176} However, requirements for long-term prophylactic therapy to prevent hemarthroses and other spontaneous hemorrhages have not been clearly defined. Three reports of prophylactic therapy in hemophilia employing widely differin...

W ARFARIN SODIUMI, 3-(alpha-acetonylbelizyl) -4-hydroxyeoumarin sodium, (Coumadini) is onie of several popular anticoagulant agents used to delay intravascular clotting by depressioni of the prothrombin level of the blood. This drug is often used iu instances in which there is an acute throinbophlebitis, pulmoniary and peripheral embolism, eoronary and cerebral thrombosis, and it is employed pr...

BACKGROUND Increase in hip intra-capsular pressure has been implicated in various hip pathologies, such as avascular necrosis complicating undisplaced femoral neck fracture. Our study aimed at documenting the relationship between intra-capsular volume and pressure in various hip positions. METHODS Fifty-two cadaveric hips were studied. An electronic pressure-monitoring catheter recorded the i...

Haemophilia A is an X-linked disorder caused by a deficiency of factor VIII. Haemorrhage in various sites may occur spontaneously or secondary to trauma depending on the severity of the deficiency. Common manifestations include haemarthrosis, epistaxis, gastrointestinal haemorrhage and haematuria. Spontaneous haemothorax has rarely been reported both in children and adults1,2. We report the cas...

Introduction. Hemophilia is an X-linked hereditary blood clotting disorder caused by insufficiency of factor VIII or IX that affects mainly men. In extremely rare cases, the disease can be observed in women, which most often associated with asymmetric inactivation X chromosome. The severity hemophilia women does not differ from Aim – to present a clinical observation surgical treatment stage 4 ...