نتایج جستجو برای: heart injury

تعداد نتایج: 689224  

Journal: :American Journal of Physiology-Heart and Circulatory Physiology 2008

2010
M. Boerma M. Hauer-Jensen

Radiation-induced heart disease (RIHD) is a potentially severe side effect of radiotherapy of thoracic and chest wall tumors if all or part of the heart was included in the radiation field. RIHD presents clinically several years after irradiation and manifestations include accelerated atherosclerosis, pericardial and myocardial fibrosis, conduction abnormalities, and injury to cardiac valves. T...

Journal: :Autonomic neuroscience : basic & clinical 2008
Yunxia Wang Guiling Li Shangdong Liang Aixia Zhang Changshui Xu Yun Gao Chunping Zhang Fang Wan

Extracellular ATP acts on purinergic receptors as a potent agonist for a variety of different cell types, including cardiomyocytes and nodose ganglia. P2X3 receptor is the most abundant P2X-receptor subtype in heart and nodose ganglia. This study wants to observe the role of P2X3 receptor in myocardial ischemic injury and nociceptive transmission via nodose ganglia. The serum lactate dehydrogen...

2016
Sophie Rodius Ganna Androsova Lou Götz Robin Liechti Isaac Crespo Susanne Merz Petr V. Nazarov Niek de Klein Céline Jeanty Juan M. González-Rosa Arnaud Muller Francois Bernardin Simone P. Niclou Laurent Vallar Nadia Mercader Mark Ibberson Ioannis Xenarios Francisco Azuaje

The zebrafish has the capacity to regenerate its heart after severe injury. While the function of a few genes during this process has been studied, we are far from fully understanding how genes interact to coordinate heart regeneration. To enable systematic insights into this phenomenon, we generated and integrated a dynamic co-expression network of heart regeneration in the zebrafish and linke...

Journal: :iranian biomedical journal 0
حمید نجفی پور hamid najafipour علی سیاه پشت خاچکی ali siahposht khachaki محمد خاکساری mohammad khaksari بید الله شاهوزهی beydolah shahouzehi سیاوش جوکار siyavash joukar حمیدرضا پورصالحی hamid reza poursalehi

background: accidents are the second reason for mortality and morbidity in iran. among them, brain injuries are the most important damage. clarification of the effects of brain injuries on different body systems will help physicians to prioritize their treatment strategies. in this study, the effect of pure brain trauma on the cardiovascular system and lungs 24 hours post trauma was assessed. m...

2016
Itsuro KAZAMA

To mimic ischemic heart disease in humans, several animal models have been created, mainly in rodents by surgically ligating their coronary arteries. In the present study, by simply inducing burn injuries on the bullfrog heart, we reproduced abnormal ST segment changes in the electrocardiogram (ECG), mimicking those observed in ischemic heart disease, such as acute myocardial infarction and ang...

Journal: :Circulation 2012
Nobuyuki Ishibashi Joseph Scafidi Akira Murata Ludmila Korotcova David Zurakowski Vittorio Gallo Richard A Jonas

BACKGROUND Neurodevelopmental delays in motor skills and white matter (WM) injury have been documented in congenital heart disease and after pediatric cardiac surgery. The lack of a suitable animal model has hampered our understanding of the cellular mechanisms underlying WM injury in these patients. Our aim is to identify an optimal surgical strategy for WM protection to reduce neurological in...

2012
Cristiano Marcelo Espinola Carvalho Jaline Coutinho Silverio Andrea Alice da Silva Isabela Resende Pereira Janice Mery Chicarino Coelho Constança Carvalho Britto Otacílio Cruz Moreira Renato Sergio Marchevsky Sergio Salles Xavier Ricardo Tostes Gazzinelli Maria da Glória Bonecini-Almeida Joseli Lannes-Vieira

BACKGROUND The factors contributing to chronic Chagas' heart disease remain unknown. High nitric oxide (NO) levels have been shown to be associated with cardiomyopathy severity in patients. Further, NO produced via inducible nitric oxide synthase (iNOS/NOS2) is proposed to play a role in Trypanosoma cruzi control. However, the participation of iNOS/NOS2 and NO in T. cruzi control and heart inju...

2013
SA Loer RA Bouwman

6 Western diet modulates the susceptibility of the heart to ischemic injury and sevoflurane-induced cardioprotection in rats Effect of diet and sevoflurane on ischemic injury 111 Abstract Introduction

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