• Keports of support of the heart in acute failure both in man and in experimental animals" have been published. The means investigated include: (1) heart-lung bypass, from the cava through an oxygenator and pump to the aorta;'" (2) veno-arterial pumping without oxygenator ; ' ' ' 3 ' 4 > (3) aortic synchronized counter pulsation to lower the pressure during left ventricular ejection and to rai...

We read with interest Hawasli et al. report of a pleomorphic sarcoma metastatic to the left atrium. However, we suspect that the true site of origin is unknown, and may in fact be the heart. There are several reasons for this: the histological appearance is similar to left atrial tumors that have already been reported; the left atrium, is the most common site of cardiac pleomorphic sarcoma; all...

Gerbode defects are a very rare anomalies, characterized by direct communication between left ventricle (LV) and right atrium (RA). Most congenital, but they can also be acquired following destructive heart diseases, such as infective endocarditis, myocardial infarction, trauma, or cardiac surgery. In this paper, we report the case of 35 years-old patient hospitalized for management an endocard...

Fetal arrythmia is reported to affect 1-2% of pregnancies. Besides digoxin not many drugs have been tried in treating such cases. After confirming 1:1 conduction between atrium and ventricle, no structural heart disease fetus normal echocardiography ECG mother, verapamil was given the treatment fetal supraventricular tachycardia. The drug crossed placenta revert SVT sinus rhythm without harming...

By using excised postmortem hearts obtained from 15 mongrel dogs with the pericardium intact, we investigated mechanical interactions between the four heart chambers from the standpoint of ventricular pressure-volume relationships. The interactions investigated were those between (1) the atrium and the ventricle, (2) the right ventricle and left ventricles, (3) the atrium and one ventricle vs. ...

A unique case is described in which infective endocarditis of the aortic valve led to intractable heart failure and necropsy examination showed that the patient had developed a communication between the left ventricle and right atrium.

A 35-year-old male patient presented with heart failure. On examination, there was a continuous murmur over the left sternum. Transthoracic echocardiography revealed a ruptured aneurysm arising from the noncoronary sinus of Valsalva and draining into the right atrium.

Background: Chronic pressure overload predisposes to heart failure, but the pathogenic role of microvascular endothelial cells (MiVEC) remains unknown. We characterized transcriptional, metabolic, and functional adaptation cardiac MiVEC in mice patients with aortic stenosis (AS). Methods: In Tie2-Gfp subjected transverse constriction or sham surgery, we performed RNA sequencing isolated Gfp + -...