Dabigatran is a direct thrombin inhibitor indicated for thromboembolism prophylaxis in patients with non-valvular atrial fibrillation. The procedure to manage dabigatran-associated haemorrhages is not well formalized. Conventional haemodialysis has been evaluated with good results. Patients with dabigatran-associated bleeding may be unstable and convective techniques like venovenous haemodiafil...

We report on some aspects of our efforts to establish properties of the extremely faint galaxy population by applying our photometric redshift technique to the HDF and HDF–S WFPC2 and NICMOS fields. We find that cosmological surface brightness dimming effects play a dominant role in setting what is observed at redshifts z > 2, that the comoving number density of high intrinsic surface brightnes...

cally appearing after her HD sessions. At that time she was treated with postdilutional HDF, with 20 l infusate per 4.5-hour session, FX80 dialyzer (helixone, 1.8 m 2 , Fresenius Medical Care, Bad Homburg, Germany), blood flow 300 ml/min, AVF as vascular access. Valproate concentrations were measured before and after HDF approximately every 2 weeks and were 666 8 53 (range 567–750, therapeutic ...

The optimal anticoagulation regimen for hemodialysis (HD) in patients with heparin-induced thrombocytopenia (HIT) has not been defined. Hemodiafiltration (HDF) adds a large convective component to HD, thereby changing the pharmacokinetics of most anticoagulants. Data on coagulation regimens for HDF are scant. We therefore aimed to study the feasibility, effectiveness, tolerability, and pharmaco...

BACKGROUND Advanced glycation end products (AGEs) accumulate in patients with end-stage renal disease (ESRD). The aim of this study was to investigate the potential influence of different modalities of renal replacement therapies on plasma AGE levels. METHODS The removal of AGEs by high-flux haemodialysis (HD) using standard and ultrapure dialysis fluid (SDF and UDF), by haemodiafiltration (H...

A variety of subtle, and not-so-subtle selection effects influence the interpretation of galaxy counts, sizes and redshift distributions in the Hubble Deep Field. Comparison of the different HDF catalogs available in the literature and on the world-wide-web reveals generally good agreement, although the effects of different isophotal thresholds and different splitting algorithms are readily app...

We present preliminary results from a programme to obtain multi-object nearinfrared spectroscopy of galaxies at redshifts 0.7 < z < 1.5. We are using the instrument CIRPASS (the Cambridge Infra-Red PAnoramic Survey Spectrograph), in multi-object mode, to survey Hα in galaxies at z ∼ 1. We aim to address the true star formation history of the universe at this epoch: potentially the peak period o...