background & aims: prevalence of uremic itch is 30% in patients on dialysis, and routine treatments are often ineffective.   materials & methods: we selected 40 hd patients and prescribed 100 mg gabapentin after each hd session for 20, and prescribe placebo for the other 20 patients. initial dose of gabapentin was 100mg after every thrice-weekly hd and altered the administered dose in the base ...

Aims. We present the results of near-infrared, follow-up imaging and spectroscopic observations at VLT, aimed at characterizing the long-period companions of the exoplanet host stars HD 196885, HD 1237 and HD 27442. The three companions were previously discovered in the course of our CFHT and VLT coronographic imaging survey dedicated to the search for faint companions of exoplanet host stars. ...

Transgenic nonhuman primate models are an increasingly popular model for neurologic and neurodegenerative disease because their brain functions and neural anatomies closely resemble those of humans. Transgenic Huntington's disease monkeys (HD monkeys) developed clinical features similar to those seen in HD patients, making the monkeys suitable for a preclinical study of HD. However, until HD mo...

AIMS Both strain and strain rate (SR) measure the regional myocardial deformation and can assess phasic left atrial (LA) function. However, there is still a lack of evidence for their volume independency. In this study, strain and SR determined by tissue Doppler imaging were used to evaluate the effect of preload reduction in end-stage renal disease patients who were undergoing regular haemodia...

In Huntington’s disease (HD), the presence of neurodegeneration in brain regions other than the striatum has been recently gaining attention. The amygdala is one such area, which has been investigated in only eight structural magnetic resonance imaging studies to date, but with inconsistent findings. This is the largest MRI study to date examining manually traced amygdala volumes in HD particip...

BACKGROUND Pulmonary arterial hypertension (PAH) is common disease among hemodialysis (HD) patients and is associated with increased morbidity and mortality. However, its pathogenesis has not been completely elucidated. We aimed to evaluate the frequency of PAH in HD patients, as well as the relationship between fluid status and PAH. MATERIAL AND METHODS We enrolled 77 HD patients in this study...

OBJECTIVE To evaluate the efficacy of rituximab (R) when added to high-dose methotrexate (HD-MTX) in patients with newly diagnosed immunocompetent primary CNS lymphomas (PCNSLs). METHODS Immunocompetent adults with newly diagnosed PCNSL treated at The Johns Hopkins Hospital between 1995 and 2012 were investigated. From 1995 to 2008, patients received HD-MTX monotherapy (8 g/m2 initially every...