To minimize network latency and remain online during server failures and network partitions, many modern distributed data storage systems eschew transactional functionality, which provides strong semantic guarantees for groups of multiple operations over multiple data items. In this work, we consider the problem of providing Highly Available Transactions (HATs): transactional guarantees that do...

In [k] = [k]×[k]× · · · ×[k], a coordinate line consists of the collection of points where all but one coordinate is fixed and the unfixed coordinate varies over all possibilities. We consider the problem of marking (or designating) one point on each line in [k] so that each point in [k] is marked either a or b times, for some fixed a or b. This is equivalent to forming a strategy for a hat gue...

We describe the development of a speech recognition system for conversational telephone speech (CTS) that incorporates acoustic features estimated by multilayer perceptrons (MLP). The acoustic features are based on frame-level phone posterior probabilities, obtained by merging two different MLP estimators, one based on PLP-Tandem features, the other based on hidden activation TRAPs (HATs) featu...

Epigenetic regulation of neuronal signalling through histone acetylation dictates transcription programs that govern neuronal memory, plasticity and learning paradigms. Histone Acetyl Transferases (HATs) and Histone Deacetylases (HDACs) are antagonistic enzymes that regulate gene expression through acetylation and deacetylation of histone proteins around which DNA is wrapped inside a eukaryotic...

Hat problems have recently become a popular topic in combinatorics and discrete mathematics. These have been shown to be strongly related to coding theory, network coding, and auctions. We consider the following version of the hat game, introduced by Winkler and studied by Butler et al. A team is composed of several players; each player is assigned a hat of a given colour; they do not see their...

We report the cloning of a transcription-associated histone acetyltransferase type A(HAT A). This Tetrahymena enzyme is strikingly homologous to the yeast protein Gcn5, a putative transcriptional adaptor, and we demonstrate that recombinant Gcn5p possesses HAT activity. Both the ciliate enzyme and Gcn5p contain potential active site residues found in other acetyltransferases and a highly conser...

Thrombocytopenia is a well- recognized complication of heparin therapy. The diagnosis is mostly clinical and the main value of laboratory testing is in excluding the diagnosis. We describe here a patient with stroke who had aspiration pneumonia leading to sepsis. She developed atrial fibrillation and received heparin which had to be stopped prematurely due to melena. Within 5 days of heparin, s...

To minimize network latency and remain online during server failures and network partitions, many modern distributed data storage systems eschew transactional functionality, which provides strong semantic guarantees for groups of multiple operations over multiple data items. In this work, we consider the problem of providing Highly Available Transactions (HATs): transactional guarantees that do...