نتایج جستجو برای: haplotype diversity

تعداد نتایج: 201547  

Journal: :Memorias do Instituto Oswaldo Cruz 2012
Gauri Awasthi Godavarthi Bhogendra Krishna Satya Prasad Aparup Das

Mutations in the Pfcrt gene that change the resulting amino acids and form different haplotypes are common and correlate with the prevalence of chloroquine resistant (CQR) field isolates of the malaria parasite, Plasmodium falciparum. This correlation provides opportunities to infer the global evolutionary history of CQ resistance by analysing CQR Pfcrt haplotype data. We collated data on the P...

Journal: :Science 2001
N Patil A J Berno D A Hinds W A Barrett J M Doshi C R Hacker C R Kautzer D H Lee C Marjoribanks D P McDonough B T Nguyen M C Norris J B Sheehan N Shen D Stern R P Stokowski D J Thomas M O Trulson K R Vyas K A Frazer S P Fodor D R Cox

Global patterns of human DNA sequence variation (haplotypes) defined by common single nucleotide polymorphisms (SNPs) have important implications for identifying disease associations and human traits. We have used high-density oligonucleotide arrays, in combination with somatic cell genetics, to identify a large fraction of all common human chromosome 21 SNPs and to directly observe the haploty...

The cysteine-rich 8K protein of Potato mop-top virus (PMTV) suppresses host RNA silencing. In this study, evolutionary analysisof 8K sequences of PMTV isolates was studied on the basis of nucleotide and amino acid sequences. Twenty-one positively selected sites were identified in 8K codingregions. Recombination events were found in the 8K of PMTV isolates with a rate of 1.8. Totally 30 haplotyp...

2017
Patrícia Ianella Maria do Socorro Maués Albuquerque Samuel Rezende Paiva Andréa Alves do Egito Leonardo Daniel Almeida Fabiana T. P. S. Sereno Luiz Felipe Ramos Carvalho Arthur da Silva Mariante Concepta Margaret McManus

The first horses were brought to Brazil by the colonizers after 1534. Over the centuries, these animals evolved and adapted to local environmental conditions usually unsuitable for exotic breeds, thereby originating locally adapted Brazilian breeds. The present work represents the first description of maternal genetic diversity in these horse breeds based on D-loop sequences. A D-Loop HSV-I fra...

Journal: :Alcoholism, clinical and experimental research 2005
Yi Han Hiroki Oota Michael V Osier Andrew J Pakstis William C Speed Adekunle Odunsi Friday Okonofua Sylvester L B Kajuna Nganyirwa J Karoma Selemani Kungulilo Elena Grigorenko Olga V Zhukova Batsheva Bonne-Tamir Ru-B Lu Josef Parnas Leslie O Schulz Judith R Kidd Kenneth K Kidd

BACKGROUND Of the seven known human alcohol dehydrogenase (ADH) genes, the non-liver expressed ADH7 gene codes for the enzyme with the highest maximal activity for ethanol. Previous study from our laboratory has suggested that ADH7 has an epistatic role for protection against alcoholism based on a single ADH7 SNP. METHODS We have now studied seven SNPs, additional populations for the SNP prev...

2014
Erick C. Castelli Jaqueline Ramalho Iane O. P. Porto Thálitta H. A. Lima Leandro P. Felício Audrey Sabbagh Eduardo A. Donadi Celso T. Mendes-Junior

Human leukocyte antigen G (HLA-G) belongs to the family of non-classical HLA class I genes, located within the major histocompatibility complex (MHC). HLA-G has been the target of most recent research regarding the function of class I non-classical genes. The main features that distinguish HLA-G from classical class I genes are (a) limited protein variability, (b) alternative splicing generatin...

Journal: :Fishes 2023

The upper reaches of the Yangtze River (upper YR) are a biological zone with extremely rich fish diversity, especially endemic fish. However, long-term human interference, such as environmental pollution and cascade hydropower construction, has significantly changed habitat many is threatening number genetic diversity populations. Jinshaia sinensis typical small but rare that found in YR, its s...

Journal: :The Journal of heredity 2015
Angus Macgregor Myburgh Savel R Daniels

Evolutionary relationships in the velvet worm species, Peripatopsis overbergiensis, were examined in 3 forest areas in the Overberg region of South Africa to explore the impact of historical habitat fragmentation on the population genetic structure of the species. We collected 84 P. overbergiensis specimens from Grootvadersbosch, Koppie Alleen, and Marloth Nature Reserves and sequenced all thes...

Journal: :Forensic science international 2005
Lotfi Cherni Luísa Pereira Ana Goios Besma Yacoubi Loueslati Houssein Khodjet el Khil Iva Gomes Leonor Gusmão Cíntia Alves Abdelhakim Slama António Amorim Amel BenAmmar Elgaaied

The 11 Y-chromosomal short tandem repeats (STRs) included in the Promega Corporation PowerPlex Y System (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385, DYS437, DYS438 and DYS439) were typed in three ethnic groups ("Andalusians", Berber and Arab) and one cosmopolitan population (Tunis) from Tunisia, summing up 247 individuals, and 139 different haplotypes. Focusing the analysi...

2014
Anila Hoda Ylli Biçoku Petrit Dobi

Albanian farmers have a long tradition in goat farming. Recently, several studies were carried out to determine genetic diversity of local goat populations, using molecular markers such as SNP (Single Nucleotide Polymorphisms), microsatellites and AFLP (Amplified Fragment Length Polymorphism). In the present study 77 mtDNA D-loop sequences from six different goat breeds were analysed. The resul...

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