allergic diseases are frequent in children and their prevalence and severity deffer in the different regions of the world. a number of studies have been performed to determine the factors which are effective in the incidence of these diseases. one of the drugs that might have a role in incidence or intensity of the symptoms of allergic diseases is acetaminophen. in our survey conducted with sta...

This paper presents a summary of the evidence review group (ERG) report into the clinical effectiveness and cost-effectiveness of alitretinoin for the treatment of adults with severe chronic hand eczema refractory to topical steroid treatment in accordance with the licensed indication, based upon the evidence submission from Basilea Pharmaceuticals Ltd to the National Institute for Health and C...

Topical corticosteroids (TCs) are the pillars of dermatotherapeutics. These drugs are the "magic molecules," provided they are used judiciously and appropriately, following a rational prescription. On exhaustive literature search in multiple databases, we found a significant evidence favoring the use of TCs in atopic eczema, localized vitiligo, psoriasis, chronic hand eczema, and localized bull...

Skin prick tests are the first investigation in allergy diagnostics and their use is described in all the guidelines on atopic eczema. However, the clinical usefulness of skin prick tests is the subject of great debate. On the one hand, skin prick tests allow the identification both of individuals at risk for food allergy and of the allergen inducing the eczematous flare. On the other hand, whe...

Process data give important insights into how an intervention is implemented. The aim of the present study is to conduct a process evaluation, alongside a randomised controlled trail, on the implementation of recommendations for the prevention of hand eczema. The intervention was carried out in healthcare workers' departments and consisted of working groups and role models. The role models were...

Hand eczema is a disease with a potentially profound effect on an individual’s life in terms of daily functioning and interpersonal relationships. Accordingly, methods for measuring health-related quality of life (QoL) are increasingly used to evaluate the effect of various treatments. In studies of skin diseases the most widely used dermatology-specific questionnaire is the Dermatology Life Qu...

BUMC PROCEEDINGS 2004;17:211–213 In mid 2002, we examined a 22-year-old waitress who complained of a 5to 6-month history of painful, pruritic lesions on her hands, arms, and legs. The itch often disturbed her sleep, and her quality of life was diminished by physical discomfort and feelings of embarrassment. Lesions on both palms showed minimal vesiculation, moderate papulation and scaling, mode...