BACKGROUND Primary Helicobacter pylori (H. pylori) infection occurs predominantly in childhood. Antimicrobial resistance is the leading cause for H. pylori eradication failure. The aims of this study were (i) to establish for the first time the antimicrobial resistance of H. pylori strains in infected Slovenian children not previously treated for H. pylori infection and (ii) to evaluate the eff...

Helicobacter pylori gastritis infection rate increases with age. Higher rates have however been reported among young people in the developing countries of the world. The infection however has rarely been reported in infants, especially in Africa. This case series describes three cases of Helicobacter pylori gastritis infection as diagnosed in three infants. The goal is to raise the suspicion in...

Helicobacter pylori is one of the most frequently occurring and persistent bacterial infections worldwide. H. pylori bacteria are associated with peptic ulcer disease, mucosaassociated lymphoid tissue lymphoma, and gastric cancer. Various diagnostic methods are used to detect H. pylori infection. However, only highly accurate tests with 90% sensitivity and 90% specificity should be used in clin...

BACKGROUND The purpose of this study is to compare validity of 5 diagnostic tests of helicobacter pylori with each other: stool antigen test, urea breath test (UBT), rapid urease test (RUT), serology and histology. METHODS A total of 94 patients who had indication of endoscopy entered the study. All of the 5 tests were performed for each patient. When the results of at least 2 tests were posi...

BACKGROUND Many of the pathogenic effects of Helicobacter pylori infection are related to chronic active inflammation, which is controlled and maintained by the complex interplay of pro-inflammatory and anti-inflammatory mediators. Pro-inflammatory genetic polymorphisms tend to increase the risk of development of gastric cancer. In Africa, the data are scarce regarding the effects of these poly...

BACKGROUND AND AIM Helicobacter pylori eradication clearly decreases peptic ulcer recurrence rates. H. pylori eradication is achieved in 70-90% of cases, but treatment failures due to poor patient compliance and resistant organisms do occur. Lactobacillus gasseri can suppress both clarithromycin-susceptible and -resistant strains of H. pylori in vitro. The aim of this study was to determine the...

BACKGROUND Helicobacter pylori, a widespread infection particularly in developing countries has been associated with many adverse effects during pregnancy including hyperemesis gravidarum, neural tube defects in newborns, intrauterine fetal growth restriction and miscarriage. We sought to document the effects of H. pylori infection on birth weight in a low-income setting in Kampala, Uganda. M...

OBJECTIVE Helicobacter pylori is recognized as a major etiological factor in the pathogenesis of gastritis and peptic ulcer disease. H. Pylori eradication has a failure rate of more than 30% in pediatric patients, particularly because of poor compliance, antibiotic resistance and occurrence of side-effects. This study was aimed to determine whether adding the probiotics to a standard anti-H. py...

Glaucoma is a neurodegenerative disease characterized by retinal ganglion cell degeneration. Although glaucoma is prevalent worldwide, its etiopathogenesis remains incompletely understood. Increased intraocular pressure (IOP) is the most frequently implied cause for retinal ganglion cell degeneration. Recent studies show that cytokines, impaired ocular blood flow, and structural changes in bloo...

Even though half of the world’s population is infected with Helicobacter pylori, which causes gastritis, peptic ulcer and gastric cancer, the transmission routes of these bacteria remain unknown despite extensive epidemiological studies. Enterotoxigenic Escherichia coli (ETEC) and Vibrio cholerae are two of the most common causes of acute watery diarrhea in developing countries. The main aim of...