Background: Risk of recurrent bleeding from Helicobacter pylori-negative ulcers is greater than for H pylori ulcers, but to what degree is unknown. Objective: To determine the risk of rebleeding for peptic ulcers with and without associated H pylori infection. Design: Prospective cohort study in 1 institution over 7 years. Participants: 120 patients had H pylori-negative peptic ulcer bleeding a...

INTRODUCTION Although it is incontrovertible that Helicobacter pylori causes peptic ulcer disease, controversy persists regarding the impact of H. pylori infection on the incidence of NSAID-related complications and whether H. pylori eradication reduces the rate of adverse events. METHODS A symptom-driven decision analytic model was developed to compare the clinical and economic impact of H. ...

Background: Chronic idiopathic urticaria is defined as urticaria, which lasts for more than 8 weeks and has no apparent etiology. The aim of this study was to examine the causal role of Helicobacter pylori infection in chronic idiopathic urticaria. Methods: Fifty-six patients with chronic idiopathic urticaria and a negative response to skin prick test for common aeroallergens were selected. The...

We read the paper written by Razeghinejad et al. (1), who conducted a study on anti- Helicobacter pylori (H. pylori) IgG antibody levels in an Iranian glaucoma cohort, with considerable interest and based on our original concept (2-5). The authors concluded that a relation between H. pylori infection and primary open-angle glaucoma is not supported by their results, because the aqueous anti- H....

Background and Objective: Host genetic factors such as cytokine gene polymorphisms as well as Helicobacter pylori (H. pylori) infection have been found to be associated with gastric cancer risk . Interleukin 1 is a pro-inflammatory cytokine involved in H. pylori-induced gastric inflammation. Therefore, w...

Previous studies suggested that polymorphisms of proinflammatory cytokine genes are important host genetic factors in Helicobacter pylori infection. The present study evaluated whether IL-8-251 polymorphism affected H. pylori eradication rate and to investigate the effect of H. pylori eradication on angiogenesis and the inflammatory process according to the IL-8-251 polymorphism. A total of 250...

helicobacter pylori (h. pylori) plays an important role in the development of peptic and duodenal ulcerations as well as gastric cancer. several studies have shown a strong association between specific genotypes of h. pylori and gastrointestinal tract diseases. the vaca and caga genes, which are the putative virulence factors of the bacterium, are important determinants of h. pylori-related dis...

Background Non-Steroidal Anti-Inflammatory Drugs(NSAIDs) including Ibuprofen is one of the most currently used drugs in all age groups and finding the relation between upper gastrointestinal bleeding and Helicobacter pylori (H. pylori) in children who used Ibuprofen, is our topic of research. Materials and Methods During the two years of the study, ten children with upper GI bleeding after Ibup...

background: helicobacter pylori ( h. pylori ) is a global pathogen with a widely varied prevalence (30%-80%) among different countries and populations. this study aims to determine the prevalence of h. pylori in the population of arak, iran. materials and methods: this was an epidemiologic cross-sectional population-based study with multistage sampling. the population of arak according to the 2...

background: otitis media with effusion (ome) is a common disease in children. viral or bacterial infections, allergy, adenoids, functional abnormalities of the eustachian tube, and gastroesophageal reflux might have a possible role in the pathogenesis of ome. however, the exact pathogenesis of ome is still unsettled. objectives: the purpose of this study was to compare helicobacter pylori preva...