Ovarian cancer accounts for the highest mortality among gynecologic cancers, mainly due to intrinsic or acquired chemoresistance. While mechanistic-based methods have been used to identify compounds that can overcome chemoresistance, an effective comprehensive drug screening has yet to be developed. We applied a transcriptome based drug sensitivity prediction method, to the Cancer Genome Atlas ...

Radiation therapy has been an effective therapeutic modality in the management of both benign and malignant tumors for over a century. The science and technology surrounding the deliv-ery of this targeted treatment has significantly improved our ability to not only control tumors, but to also minimize the untoward complications of irradiating normal tissues. Advances in radia-tion and surgical ...

female cancer, especially breast and gynecologic cancers are considered multistage disease, highly influenced by risk and protective factors and/or screening preventive modalities. consequences of all these factors result in the trend of change over time.in this comparative study, based on data of national cancer registry of iran 2004 published by iranian ministry of health, age - standard inci...

background pain following laparoscopy could be due to different causes requiring effective postoperative analgesia. objectives in the present study, we evaluated the combined effect of intraperitoneal infiltration of bupivacaine-meperidine versus intravenous infusion of paracetamol on pain relief after diagnostic gynecologic laparoscopy. conclusions intraperitoneal infiltration of bupivacaine w...

OBJECTIVE To identify potential cost savings in gynecologic oncology care without sacrificing quality. METHODS Members of the Clinical Practice Committee of the Society of Gynecologic Oncology were asked to review current practice patterns in gynecologic oncology and assess the potential for cost savings founded on evidence-based medicine and current guidelines. RESULTS Five clinical practi...

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To further delineate specific staining patterns and refine the differential usefulness of cytokeratin (CK) 7/20 staining, we studied multiple ovarian tumors and primary nongynecologic neoplasms likely to metastasize to the ovary. Immunohistochemical analysis with semiquantitative grading to give quartile scores (0-4) was performed on 127 cases. Subsequent analysis indicated that a more informat...

Synapse. The journal aims to become a representative journal in gynecologic oncology in the region of Asia and Oceania. One of the leading SCI(E) journals in gynecologic oncology is 'Gynecologic Oncology' (GO), which was launched in 1972 and has been published by the Society of Gynecologic Oncol­ ogy (SGO). Another is 'International Journal of Gynecological Cancer' (IJGC), launched in 1991 as a...

OBJECTIVES To evaluate the satisfaction with work-life balance (WLB) and career satisfaction of gynecologic oncologists. METHODS In August 2014, members of the Society of Gynecologic Oncology (SGO) were sent an anonymous, cross-sectional survey evaluating demographic variables, practice characteristics, career satisfaction, fatigue, and satisfaction with WLB. Fatigue was assessed using a visu...