By means of an ensemble Monte Carlo simulator, the appeareance of THz oscillations in InAlAs/InGaAs slot diodes is predicted when the applied bias exceeds the threshold for intervalley transfer. Such high frequency is attained by the presence of a Gunn-like effect in the recess-to-drain region of the device channel whose dynamics is controlled by ballistic  valley electrons. In this work we ex...

Mild constitutive hyperbilirubinemia is associated with a reduced risk of cardiovascular diseases, diabetes, and cancer. Since these pathologies are associated with aging, inflammation, and oxidative stress, we investigated whether hyperbilirubinemia interferes with ROS homeostasis in cell cultures and with inflammation, senescence, and mitochondrial dysfunction in aged rats. Human embryonic ki...

Gunn rats glucuronidate acetaminophen (APAP) at reduced rates and show increased susceptibility to APAP-induced hepatotoxicity. This defect is presumed to involve UDP-glucuronosyltransferase (UGT) 1A6, which is nonfunctional in Gunn rats, but it is currently unclear whether other 1A family members are also involved. In humans, two 1A isoforms are known to be active (1A6 and 1A9) but 1A6 form ha...

BACKGROUND AND AIMS Several conditions that delay gastrointestinal transit are associated with unconjugated hyperbilirubinaemia. We hypothesised that the gastrointestinal transit time is directly related to plasma unconjugated bilirubin (UCB) concentrations, and that this relationship can be used to develop a new therapeutic strategy for severe unconjugated hyperbilirubinaemia in the Gunn rat m...

Gunn rats, which have defects in bilirubin and 4-nitrophenol UDP-glucuronyltransferases (GT), were crossed with LA Wistar rats with a defect in androsterone GT. The F1 hybrids showed normal GT activities towards androsterone, bilirubin and 4-nitrophenol, demonstrating that Gunn and LA ('low activity') Wistar rats inherit a homozygous dominant trait for androsterone GT and bilirubin GT respectiv...

Introduction: Residual oxygen-free radicals of bleaching agents before composite restorations can increase microleakage in enamel and dentin margins, and also various bleaching techniques are being developed using light sources. The present study was conducted to compare the effect of diode laser bleaching and LED activated bleaching on the microleakage of composite restorations. Materials & M...

Nonlinear dynamics in Gunn devices that can exhibit chaotic behaviour is discussed. Evidence for such behaviour is given by laboratory experiments, by computer simulations, and, where available, by simple mathematical reasoning.

introduction: the aim of the present study was to investigate the effects of srp assisted by the two clinical treatment methods of diode laser or chlorhexidine gel applications in comparison with srp alone. methods: eight patients with moderate to severe chronic periodontitis, each with at least three pockets 4–7 mm deep, were selected for this study. over 66 pockets were selected and randomly ...

introduction: the aim of this study was to compare the antibacterial efficacy of diode laser 810nm and photodynamic therapy (pdt) in reducing bacterial microflora in endodontic retreatment of teeth with periradicular lesion. methods: in this in vivo clinical trial, 20 patients who needed endodontic retreatment were selected. after conventional chemo mechanical preparation of root canals, microb...