Obesity-induced insulin resistance has been linked to adipose tissue lipid aldehyde production and protein carbonylation. Trans-4-hydroxy-2-nonenal (4-HNE) is the most abundant lipid aldehyde in murine adipose tissue and is metabolized by glutathione S-transferase A4 (GSTA4), producing glutathionyl-HNE (GS-HNE) and its metabolite glutathionyl-1,4-dihydroxynonene (GS-DHN). The objective of this ...

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In 2009 and 2010 the L-band microwave Cooperative Airborne Radiometer for Ocean and Land Studies (CAROLS) campaign was performed in southwestern France to support the calibration and validation of the new Soil Moisture and Ocean Salinity (SMOS) satellite mission. The Lband Microwave Emission of the Biosphere (L-MEB) model was used to retrieve surface soil moisture (SSM) and the vegetation optic...

A quantizable worldsheet action is constructed for the superstring in a supersymmetric plane wave background with Ramond-Ramond flux. The action is manifestly invariant under all isometries of the background and is an exact worldsheet conformal field theory. It has recently been recognized that the Penrose limit of the AdS 5 × S 5 background with Ramond-Ramond (R-R) flux is a supersymmetric pla...

Recent reports claimed that glucosylsphingosine (GS) is highly accumulated and specifically evoking itch-scratch responses in the skins of atopic dermatitis (AD) patients. However, it was unclear how GS can trigger itch-scratch responses, since there were no known molecular singling pathways revealed yet. In the present study, it was verified for the first time that GS can activate mouse seroto...

BACKGROUND Genomic selection or genome-wide selection (GS) has been highlighted as a new approach for marker-assisted selection (MAS) in recent years. GS is a form of MAS that selects favourable individuals based on genomic estimated breeding values. Previous studies have suggested the utility of GS, especially for capturing small-effect quantitative trait loci, but GS has not become a popular ...

The glucosinolate(GS)-myrosinase system of Brassicaceae, including the model plant Arabidopsis thaliana (L.), comprises a defence which is effective especially against generalist herbivores. Based on their side chain structure GS are grouped into aliphatic, aromatic, and indolyl GS. Indolyl GS are widely distributed among A. thaliana ecotypes and the Brassicaceae family, but the presence of ali...

Leaves from mature Griffonia supficifolia plants were examined for the presence of leaf lectins possessing sugar binding specificities similar to the four known seed lectins (GS-I, GS-II, GS-III, GS-IV). Three (GS-I, -II, -IV) of the four known G. sinpIicifofia seed lectins were present in the leaves. Leaf G. simplicifolia lectins I and IV were similar to the respective seed lectins. Leaf GS-II...

Guggulsterone (GS) [4,17(20)-pregnadiene-3,16-dione] is a phytosterol found in the gum resin of the Commiphora mukul. GS exists naturally in two stereoisomers: E-GS (cis-GS) and Z-GS (trans-GS). In this study, the effects of both isomers on expression of the cytoprotective enzyme heme oxygenase-1 (HO-1) were evaluated in human mammary epithelial (MCF10A) cells. NF-E2-related factor 2 (Nrf2) is ...