Much has been written and said in recent years regarding the classification and significance of the Enterobacteriaceae. These organisms, without a doubt, exceed all other gram-negative bacteria as etiologic agents of disease, and because of their predominance they have deserved the attention that they have received. With the emphasis placed on these fermenting bacteria, however, a dearth of inf...

The activity of a new semisynthetic penicillin, carbenicillin, was determined against 241 strains of gram-negative bacilli with the tube-dilution technique. Of 143 strains of Pseudomonas sp., 99 had a minimal inhibitory concentration of 200 to 300 mug/ml. The majority of strains of Escherichia coli and Proteus spp. were sensitive to this antibiotic, with minimal inhibitory concentrations of 25 ...

INTRODUCTION Antibiotic resistance in gram-negative bacilli is an area of increasing importance. This prospective study was performed to survey antibiotic resistance in Escherichia coli (E. coli), Klebsiella spp., Pseudomonas aeruginosa and Acinetobacter spp. over a 1-year period. MATERIALS AND METHODS Non-duplicate isolates of E. coli, Klebsiella spp., P. aeruginosa and Acinetobacter spp. we...

INTRODUCTION The prevalence of extensively drug resistant gram negative bacilli (XDR-GNB) is rapidly progressing; however in Egypt data are sparse. We conducted the present study to quantify the incidence, risk factors and outcome of patients harboring XDR-GNB. METHODS A one year prospective study was done by collecting all the bacteriological reports for cultures sent from the surgical inten...

Non fermenting gram negative bacteria were considered to be nonpathogenic and commensal of little significance. Recently there has been a tremendous interest in these organisms as they are being isolated from clinical specimens with increasing frequency. So this study aims at isolation, identification and antibiotic susceptibility of non-fermenting gram negative bacilli from various clinical sp...

Title: In vitro antibacterial activity of piperacillin versus piperacillintazobactam on gram negative clinical isolates from a tertiary care hospital.Objective :To compare in-vitro antibacterial activity of piperacillin with piperacillin-tazobactam combination on the most common isolates of gram negative bacilli obtained from various clinical samples from a tertiary care hospital. Methodology :...

The in vitro effect of trimethoprim on the inhibitory and bactericidal activity of amikacin against 20 strains each of Klebsiella pneumoniae and Serratia marcescens, 15 strains of Escherichia coli, and 10 strains of Pseudomonas aeruginosa was examined by the checkerboard technique in microtiter plates. Trimethoprim had a synergistic effect on the inhibitory and bactericidal activity of amikacin...

BACKGROUND The growing burden of neonatal mortality associated with hospital-acquired neonatal sepsis in the developing world creates an urgent need for cost-effective infection-control measures in resource-limited settings. METHODS Using a before-and-after comparison design, we measured how rates of staff hand-hygiene compliance, colonization with drug-resistant pathogens (defined as ceftazi...

The in vitro activities of Y-688, a new 7-substituted fluoroquinolone derivative, against 317 nonduplicate anaerobic isolates were determined. Eighty-five percent of the Bacteroides fragilis group (n = 89) were inhibited by < or = 2 mg of Y-688 per liter, while 78, 100, 89, and 98% of gram-negative bacilli (n = 135), gram-positive cocci (n = 59), and non-spore-forming (n = 58) and spore-forming...