Proteins containing the G protein regulator (GPR) domain bind the major neural G protein Gα(o) in vitro. However, the biological functions of GPR proteins in neurons remain undefined, and based on the in vitro activities of GPR proteins it is unclear whether these proteins activate or inhibit G protein signaling in vivo. We found that the conserved GPR domain protein AGS-3 activates Gα(o) signa...

Over the last few years high-resolution geophysical techniques, in particular ground-penetrating radar (GPR), have been used in agricultural applications for assessing soil water content variation in a non-invasive way. However, the wide use of GPR is greatly limited by the data processing complexity. In this paper, a quantitative analysis of GPR data is proposed. The data were collected with 2...

The spatial representation of accumulation measurements is a major limitation for current glacier mass balance monitoring approaches. Here, we present a method for estimating annual accumulation rates on a temperate Alpine glacier based on the interpretation of internal reflection horizons (IRHs) in helicopter-borne ground-penetrating radar (GPR) data. For each individual GPR measurement, the s...

Objectives To systematically review randomized controlled trials that assessed the effects of Global Postural Reeducation (GPR) on patient-reported outcomes in conditions of the musculoskeletal system. Method An electronic search of MEDLINE (via PubMed), EMBASE, Cochrane CENTRAL, and SciELO was performed from their inception to June 2015. Randomized controlled trials that analyzed pain and pati...

[1] Investigations of solute transport in fractured rock aquifers often rely on tracer test data acquired at a limited number of observation points. Such data do not, by themselves, allow detailed assessments of the spreading of the injected tracer plume. To better understand the transport behavior in a granitic aquifer, we combine tracer test data with single-hole ground-penetrating radar (GPR...

In order to develop and evaluate a method for the determination of glacier volume from ice-thickness data, the volume of Schaufelferner, Austria, is calculated (1) by manual interpolation of ground-penetrating radar (GPR) data based on measurements at 36 locations in 1995, (2) by manual interpolation of 144 GPR measurements acquired for a higher-resolution estimate in 2003 and 2006, (3) by mult...

Ground penetrating radar (GPR) is a widely used sensor for land mine detection. However, GPR signal return is very susceptible to ground bounce and reflection of clutter objects, which makes the detection a difficult problem to date. In this paper, we propose to utilize two-sided linear prediction (LP) to model the background interference and then employ the residue energy to generate the test ...

Biological and chemical reactions involved in physiological processes are often complex and very sophisticated. Such processes can be mimicked in the laboratory to obtain important knowledge, valuable for the development of new diagnostic methods, drugs and biosensors. This thesis includes investigations of bio-functionalized surfaces that can be used as model systems to mimic naturally existin...

Introduction: The thickness of the lunar regolith and potential for frozen water are important considerations for future lunar outposts. However, the thickness of the regolith is largely unknown and the presence of water ice has yet to be directly detected at or beneath the surface. A rapid and economical geophysical method to determine both the thickness of the lunar regolith and possibly iden...