Women are more likely to suffer an anterior cruciate ligament (ACL) rupture than men, and the incidence of ACL rupture in women rises with increasing estrogen levels. We used an engineered ligament model to determine how an acute rise in estrogen decreases the mechanical properties of ligaments. Using fibroblasts isolated from human ACLs from male or female donors, we engineered ligaments and d...

Eben Donges Hospital (EDH) is a regional hospital in the Boland/Overberg region of the Western Cape. It serves a diverse community whose economic stability is reliant on the intensive fruit-farming industry. This farming is heavily dependent on organophosphate (OP)-containing insecticides for pest control, often to the detriment of labourers’ health. The combination of accessibility, limited le...

The ability to dynamically redefine the computational base of a processor is seen as a possible approach to improving the processor's performance. Provision of a facility to allow dynamic linking and loading of microprograms is considered as a practical means of accomplishing this modification. The feasibility and the desirability of this approach is evaluated in terms of the implementation ove...

Universal Linker phosphoramidite was synthesized and employed for conversion of conventional nucleoside bound solid phase into the universal support. The latter was successfully tested in preparation of the 20mer oligonucleotide.

Sowhat is an administrative tool that performs global impact analysis of dynamic library dependencies for Solaris systems. Sowhat runs in two phases. It first builds a database of dependencies offline in the background, and then answers user queries and generates reports in real time based upon stored knowledge. Using sowhat, one can find problems with library bindings in large program reposito...

Potassium channels are integral membrane proteins that selectively transport K+ ions across cell membranes. They function through a pair of gates, which work in tandem to allow the passage of the ions through the channel pore in a coupled system, to which I refer to here as the “gate linker”. The functional mutation effects, as described in the literature, suggest that the gate linker functions...

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