hashimoto's encephalopathy (he) is a rare condition characterized by atypical psychiatric and heterogeneous neurological manifestations such as acute cerebral ischemia, seizure, tremors, myoclonus, psychosis, depression, cognitive disorders, and fluctuating loss of consciousness. here, a case of 28 year-old man was reported who referred to the emergency department (ed) with different acute neur...

the diagnosis of celiac disease (cd) relies on the concordance of pathological, serological, genetic and clinical features. for this reason, the diagnosis of cd is often a challenge. seronegative celiac disease (sncd) is defined by the negativity of anti-tissue transglutaminase antibodies in the presence of a positive histology on duodenal biopsy samples, i. e. inflammatory infiltrate of intra-...

The sera of patients with small cell carcinoma of the lung (SCCL) and an associated visual paraneoplastic syndrome (VPNS) have high titer immunoglobulins that react with retinal ganglion cells and with cloned lines of the SCCL. The immunoglobulins in the sera of two patients with SCCL and VPNS reacted with at least one common antigen shared by neural cells and cloned lines of the SCCL. The mole...

Fifty four schizophrenic patients, diagnosed as per Research Diagnostic Criteria, were studied for immunoglobulin profiles. The schizophrenics were subdivided into paranoid and non-paranoid groups and their immunoglobulin profiles were compared with those of normals. There was no significant difference between normals and schizophrenic groups. Duration of illness, previous episodes of schizopnr...

E. Richard Stiehm, MD*, Jordan S. Orange, MD, PhD, Mark Ballow, MD, Heather Lehman, MD Division of Immunology/Allergy/Rheumatology, Mattel Children’s Hospital, UCLA School of Medicine at UCLA, CA, USA Division of Immunology, Children’s Hospital of Philadelphia, University of Pennsylvania School of Medicine, PA, USA Division of Allergy, Immunology and Pediatric Rheumatology, Women & Children’s H...

Abstract Introduction: Thalassemia is the most common hereditary anemia in Iran. The aim of this study was to evaluate the humoral immune system and assess the effect of splenectomy on the serum level of immunoglobulins IgG, IgM, and IgA and complement components in patients with major thalassemia. Materials and Methods: This interventional semi-experimental study (before-after) was performed...

conclusions this preliminary study showed that patients with kd and a high kobayashi score are at greater risk of being unresponsive to ivig treatment. further studies, preferably multicenter evaluations, are required in order to understand the exact application of various scoring systems in the management of people with kd in iran. objectives to evaluate the kobayashi scoring system with regar...

background: during the last twenty years, the extraction of specific egg yolk (igy) antibodies from the immunized chickens has been accepted as a useful alternative to the immunization of mammals. the aim of the present study was immunizing the chickens with human umbilical cord serum (hucs) and the extraction of specific anti-human globulins (igg, c3b, and c3d) antibodies from egg yolk in orde...