INTRODUCTION AND OBJECTIVES The aim was to evaluate the relationship between the magnitude of the variation in the level of glycemia during hospitalization and in-hospital and long-term mortality and postdischarge endpoints in two groups of patients with acute coronary syndrome: those with and those without a previous diagnosis of diabetes. METHODS The study included 1210 patients admitted fo...

INTRODUCTION Hypoglycemia is a defining feature of severe malaria and several other infectious diseases in children but the prevalence, significance, and prognosis of abnormal blood glucose, including hyperglycemia, have rarely been addressed in severely ill children in non-malaria endemic areas. METHODS In Madagascar, consecutive children (1 month-15 years) admitted to the pediatric ward of ...

PURPOSE to evaluate factors related to the presence of neonatal macrosomia in pregnant women with gestational diabetes mellitus. METHODS 157 pregnant women presenting gestational diabetes mellitus in follow-up were retrospectively selected from January 2004 to July 2006. This group has been divided into two subgroups: one with newborns with weight in accordance with the gestational age (n=136...

INTRODUCTION There are no available data addressing the potential clinical risks of open-water swimming competitions. OBJECTIVE Address the risks of hypothermia and hypoglycemia during a 10-km open-water swimming competition in order to alert physicians to the potential dangers of this recently-introduced Olympic event. METHODS This was an observational cross-sectional study, conducted duri...

AIM The present study was undertaken to evaluate the acute and subchronic antihyperglycemic effects of methanolic extract of Bowdichia virgilioides root bark of B. virgilioides in streptozotocin (STZ)-induced diabetic rats. MATERIALS AND METHODS The extract (100, 250 or 500 mg/kg) was orally administered to male Wistar diabetic (STZ, 42 mg/kg i.v.) and non-diabetic rats into two main protocol...

BACKGROUND The validity of continuous glucose monitoring (CGM) is well established in diabetic patients. CGM is also increasingly used for research purposes in normo-glycemic individuals, but the CGM validity in such individuals is unknown. We studied the accuracy of CGM measurements in normo-glycemic individuals by comparing CGM-derived versus venous blood-derived glucose levels and measures o...

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“I f I had a world of my own, everything would be nonsense. Nothing would be what it is, because everything would be what it isn’t. And contrary wise, what is, it wouldn’t be. And what it wouldn’t be, it would.” This quote by Alice from the Disney film version of Alice in Wonderland by Lewis Carroll may make sense in the world she experiences. In our world, Alice’s wish is usually not fulfilled...

OBJECTIVE The objective of this study was to determine the relationship between A1C and glycemia in HIV infection. RESEARCH DESIGN AND METHODS We completed a prospective cross-sectional study of 100 HIV-infected adults with type 2 diabetes (77%) or fasting hyperglycemia (23%) with measured glucose, A1C, mean corpuscular volume (MCV), and fructosamine. A total of 200 HIV-uninfected type 2 diab...

Incretin treatment Visboll et al. (abstract 1465) studied 13 women with gestational diabetes mellitus during the third trimester and 2–3 months following delivery, showing almost a doubling of the insulin secretory effect of oral glucose over that of intravenous glucose, evidence of reversibility of the reduced incretin effect of type 2 diabetes with improvement in glycemia. Yokoo et al. (abstr...