Early diagnosis of GDM is necessary to reduce maternal and fetal morbidity and mortality. As all approaches to diagnosis of GDM are costly and difficult, we meant to find an appropriate and simple way to perform this test. One-thousand six-hundred and fifty-three pregnant women were screened for GDM at 24-28 weeks of gestation. Initial screening was done by a glucose challenge test with 50 g gl...

Over the years, what started as a screening to determine which pregnant women were at risk of developing diabetes later in life has changed progressively into a screening for diabetes during pregnancy. From only screening women with risk factors, the medical community has moved to a universal screening for glucose intolerance during pregnancy. Recently, the push has been to expand this screenin...

OBJECTIVE The purpose of this study was to examine trends in postpartum glucose screening for women with gestational diabetes mellitus (GDM), predictors of screening, trends in postpartum impaired fasting glucose (IFG) and diabetes, and diabetes and pre-diabetes detected by postpartum fasting plasma glucose (FPG) versus a 75-g oral glucose tolerance test (OGTT). RESEARCH DESIGN AND METHODS Th...

HIGHLIGHTS The combined use of fasting plasma glucose and hemoglobin A1c test is associated with significantly higher diagnostic rates of prediabetes across age, race/ethnicity, and BMI than using only one test.Combined use of fasting plasma glucose, hemoglobin A1c, and oral glucose tolerance test do not improve the overall and gender-specific prediabetes prevalence beyond what is observed usin...

OBJECTIVE To determine the prevalence of metabolic syndrome and insulin resistance in Thai women with polycystic ovary syndrome (PCOS). MATERIAL AND METHOD Oral glucose tolerance tests were performed in 70 PCOS women. Blood was taken for the measurement of fasting insulin, 2-hr postprandial insulin, lipid profiles, testosterone and sex hormone binding globulin RESULTS The prevalence of meta...

introduction: repeated hyperglycemia play an important role in the development of atherosclerosis in diabetic patients. endothelium is the organ of the first-line defense against atherosclerosis and nitric oxide has a major role in this task. the aim of this study was to determine changes in plasma nitric oxide metabolites concentration during glucose tolerance test in type 2 diabetic rats. met...

Polycystic ovary syndrome (PCOS) is a syndrome associated with insulin resistance (IR), obesity, infertility, and increased cardiometabolic risk. This is a descriptive review of several mechanisms that can explain the IR among women with PCOS, other risk factors for the development of diabetes, and the screening methods used for the detection of glucose intolerance in women with PCOS. Few mecha...

Aim: It was aimed to evaluate the diagnostic performance of hemoglobin A1c (HbA1c) test in pediatric prediabetes, and determine cut-off value for adolescent. 
 Material Method: This study carried out by retrospectively evaluating data 379 adolescents aged between 10 18 years. Prediabetes diagnosed based on glucose criteria, either fasting or 2-hour (2h) during a 75 g oral tolerance (OGTT),...