BACKGROUND Ingested proteins are known to stimulate a rise in insulin and glucagon concentrations. In our effort to explain this effect, we have begun to measure the effect of individual amino acids. OBJECTIVES The objectives were to determine the effect of lysine ingestion on insulin and glucagon concentrations and whether the effect is moderated by glucose ingestion. DESIGN Thirteen healt...

Decreasing the inflammatory response that leads to tissue damage during cystic fibrosis (CF) lung disease has been a long-standing goal of CF therapy. While corticosteroids are widely used anti-inflammatory drugs, their efficacy in CF lung disease remains debated. The complex interaction between the colonising bacteria and the host environment may impact corticosteroid responsiveness. In this s...

The jejunal morphological and functional response to either a gluten-free diet or corticosteroid therapy was studied in six patients with dermatitis herpetiformis. In each treatment group there were two patients with subtotal villous atrophy and one with partial villous atrophy. After treatment, in both groups, morphological improvement was seen in villous and surface cell heights, mucosal thic...

Graphene-modified Cu2O nanocomposite was synthesized under facile microwave irradiation of an aqueous solution and has been investigated as an enzyme-free glucose biosensor. Morphology and crystal structure of the graphene-modified Cu2O nanocomposite were investigated by using electron microscopy and X-Ray Diffraction (XRD) analyses. Also, the electrochemical performan...

A 24 year old woman with bilateral oral white patches was referred to dermatology clinic. Her chief complaint was mouth burning. Pathological report of cut section biopsy from oral mucosa was in favor of lichen planus. Intralesional corticosteroid injection and it's subsequent systemic administration 30 mg/ daily for one month showed no improvement. Therefore a combination of systemic corticost...

conclusions our results demonstrated no significant correlation between the ird5 lifespan and the trehalose concentration. likewise, the correlation between lifespan extension, trehalose accumulation, and cellular resistance to hydrogen peroxide was not significant. results the lifespan of the ird5 mutant was significantly longer that of either the ird11 mutant or the wild type cells. under rep...