Glucose entry, as measured by 5-min uptake into the acid-soluble fraction, is enhanced 15-30 times by long-term (12-24 hr) hexose starvation of chick fibroblasts. The rate of galactose accumulation in the cells increases only 5 times under the same conditions of starvation. Several carbon and energy sources that were tested for their effect on this "derepression" can be classified as: (i) those...

The susceptibility of four strains of Candida albicans to phagocytosis and intracellular killing by rabbit peritoneal neutrophils was investigated. Two of the strains, isolated from active infections, were known to synthesize a surface layer of mannoprotein fibrils in response to growth on 500 mm-galactose; the other strains, from asymptomatic carriers, lacked this capability. The presence of s...

The normal newborn infant has inadequate homeostatic mechanisms for stabilizing the concentration of glucose in the blood (1, 2). Recent studies of carbohydrate metabolism in this age group have indicated a diminished responsiveness to small doses (30 jug per kg body weight) of exogenous glucagon (3, 4) and a slow rate of disappearance from the blood of either glucose or galactose administered ...

The kinetics and the metabolism of Bifidobacterium adolescentis MB 239 growing on galactooligosaccharides (GOS), lactose, galactose, and glucose were investigated. An unstructured unsegregated model for growth in batch cultures was developed, and kinetic parameters were calculated with a recursive algorithm. The growth rate and cellular yield were highest on galactose, followed by lactose and G...

SVANBERG [1930] investigated the possibility that a brei made of the lactating mammary gland might synthesize lactose from added glucose or a glucosegalactose mixture. In his experiments toluene was used as a preservative, and the reducing sugars were partitioned into disaccharide and monosaccharide fractions. With one doubtful exception, the results were negative. Michlin & Lewitow [1934] carr...

The increased rate of glucose uptake found in cells transformed by Rous sarcoma virus was shown to be enhanced relative to the changes in uptake induced in nontransformed cells by deprivation of glucose (deprivation derepression). Glucose-specific uptake sites were distinguished from glucose-galactose sites in nontransformed cells, and the capacities for glucose uptake and for galactose uptake ...

Beet and cane molasses mainly contain mono- di-, tri-saccharides, composed by hexoses, as well pentoses in traces. However, rationing software consider sugars only one entity, with a rate of digestion ∼20% h−1. The aim this initial study was to investigate evaluate the vitro dynamics rates sugar fraction molasses. Three beet three were randomly selected from variety samples collected world-wide...

Lactose is usually metabolized by A-galactosidase-catalyzed cleavage to D-glucose and D-galactose, followed by the conversion of Dgalactose to D-glucose 6-phosphate via the well known Leloir pathway (10): D-galactose *D galactose 1-phosphate D-glucose 1-phosphate D-glucose 6-phosphate. In Staphylococcus aureus, however, the disaccharide is utilized exclusively via lactose phosphate, which is cl...

The disaccharide unit of the glomerular basement membrane has been studied in regard to its detailed structure and its linkage to the peptide portion. Graded acid hydrolysis of glycopeptides containing this unit resulted in a more rapid release of glucose than galactose and indicated that glucose was in the external position. Isolation of a disaccharide consisting of glucose and galactose with ...