نتایج جستجو برای: gluconeogenesis

تعداد نتایج: 3670  

Journal: :Journal of Biological Chemistry 2021

Journal: :Diabetes 2000
R S Hundal M Krssak S Dufour D Laurent V Lebon V Chandramouli S E Inzucchi W C Schumann K F Petersen B R Landau G I Shulman

To examine the mechanism by which metformin lowers endogenous glucose production in type 2 diabetic patients, we studied seven type 2 diabetic subjects, with fasting hyperglycemia (15.5 +/- 1.3 mmol/l), before and after 3 months of metformin treatment. Seven healthy subjects, matched for sex, age, and BMI, served as control subjects. Rates of net hepatic glycogenolysis, estimated by 13C nuclear...

Journal: :The American journal of clinical nutrition 2000
S Leij-Halfwerk P C Dagnelie J W van Den Berg J D Wattimena C H Hordijk-Luijk J P Wilson

BACKGROUND The role of gluconeogenesis from protein in the pathogenesis of weight loss in lung cancer is unclear. OBJECTIVE Our aim was to study gluconeogenesis from alanine in lung cancer patients and to analyze its relation to the degree of weight loss. DESIGN In this cross-sectional study, we used primed-constant infusions of [6,6-(2)H(2)]-D-glucose and [3-(13)C]-L-alanine to assess whol...

Journal: :Journal of Biological Chemistry 1969

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