Limited prospective data are available on the importance of estimated glomerular filtration rate (GFR) and proteinuria in the prediction of all-cause mortality (ACM) in community-based elderly populations. We examined the relationship between GFR or proteinuria and ACM in 949 randomly selected community-dwelling elderly subjects (aged ≥65 years) over a 5-year period. A spot urine sample was use...

Reference 1. Assi LK, McIntyre N, Fraser S, Harris S, Hutchison CA, McIntyre CW, et al. (2015) The Association between Polyclonal Combined Serum Free Light Chain Concentration and Mortality in Individuals with Early Chronic Kidney Disease. PLoS ONE 10(7): e0129980. doi:10.1371/journal.pone.0129980 PMID: 26132658 Fig 4. Correlation of cFLC and eGFR. There was a significant inverse association wi...

• There is no convincing evidence that serum cystatin C measurement offers any clinical advantage over estimated glomerular filtration rate (eGFR) (Level III evidence, small-to-medium observational cohort studies, surrogate outcomes, weak effect) except that serum cystatin C appears to be superior to both serum creatinine and eGFR as a predictor of cardiovascular events in the eldely (age ≥ 65 ...

The link between changes in a subject's metabolic syndrome components and his estimated glomerular filtration rate (eGFR) was evaluated in healthy Japanese men. We used data from 120 Japanese men (45.5 ± 8.4 years) with a 1-year follow up. eGFR was defined by a new equation developed for Japan. There were no significant differences in eGFR between men with and without metabolic syndrome compone...

PURPOSE Radical nephrectomy is inevitably associated with a variable renal function decrease. We assessed the association of histopathological parameters in nonneoplastic renal parenchyma with the renal function decrease after radical nephrectomy. MATERIALS AND METHODS We evaluated 32 male and 17 female patients with a mean age of 55.9 years who underwent laparoscopic radical nephrectomy. Usi...