نتایج جستجو برای: gleason

تعداد نتایج: 4455  

2011
Guillaume Ploussard Mohammad Ali Agamy Olivier Alenda Yves Allory Pascal Mouracade Dimitri Vordos Andras Hoznek Claude-Clément Abbou Alexandre de la Taille Laurent Salomon

for PSA failure ( P < 0.001; hazard ratio, HR, 2.6), need for salvage therapy ( P < 0.001; HR, 2.9) and specific deaths ( P = 0.006; HR, 3.7). The 5-year RFS was 84.4% in men with negative margins compared to 57.5% in the case of PSM. • After stratification by pathological stage and Gleason score, margin status was significantly predictive for PSA failure in pT2 ( P < 0.001), pT3a ( P = 0.001) ...

Journal: :Journal of Mathematical Analysis and Applications 2010

Journal: :Nature Reviews Urology 2015

Journal: :Journal of Functional Analysis 1976

2016
Kazutoshi Fujita Takuji Hayashi Kyosuke Matsuzaki Wataru Nakata Mika Masuda Atsunari Kawashima Takeshi Ujike Akira Nagahara Mutsumi Tsuchiya Yuka Kobayashi Satoshi Nojima Motohide Uemura Eiichi Morii Eiji Miyoshi Norio Nonomura

Fucosylation is an important oligosaccharide modification associated with cancer and inflammation. We investigated whether urinary fucosylated PSA (Fuc-PSA) levels could be used for the detection of high Gleason score prostate cancer. Urine samples were collected from men with abnormal digital rectal examination findings or elevated serum PSA levels, before prostate biopsy. Lectin-antibody ELIS...

2012
Peter Hammarsten Mariateresa Cipriano Andreas Josefsson Pär Stattin Lars Egevad Torvald Granfors Christopher J. Fowler

BACKGROUND In the present study, we have investigated the prognostic usefulness of phosphorylated Akt immunoreactivity (pAkt-IR) in prostate cancer using a well-characterised tissue microarray from men who had undergone transurethral resection due to lower urinary tract symptoms. METHODOLOGY/PRINCIPAL FINDINGS pAkt-IR in prostate epithelial and tumour cells was assessed using a monoclonal ant...

2014
Rodolfo Montironi Marina Scarpelli Roberta Mazzucchelli Antonio Lopez-Beltran Matteo Santoni Alberto Briganti Francesco Montorsi Liang Cheng

BACKGROUND There is a worldwide debate involving clinicians, uropathologists as well as patients and their families on whether Gleason score 6 adenocarcinoma should be labelled as cancer. CASE DESCRIPTION We report a case of man diagnosed with biopsy Gleason score 6 acinar adenocarcinoma and classified as low risk (based on a PSA of 5 ng/mL and stage cT2a) whose radical prostatectomy specimen...

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