Giriş ve Amaç: Çalışmamızın amacı, gestasyonel trofoblastik hastalık (GTH) tanısı alan hastalarımızın insidansını, demografik özelliklerini, komplikasyonlarını, takip tedavi yaklaşımlarını güncel literatür bilgileriyle tartışılmasıdır.
 Gereç Yöntemler: Kliniğimizde 2005- 2020 tarihleri arasında histopatolojik olarak GTH 134 hasta geriye dönük çalışmaya alındı. Bu hastaların başvuru şikâye...

Molar pregnancies can be subdivided into complete (CM) and partial moles (PM) based on genetic and histopathological features. Complete moles are diploid and androgenic in origin, with no evidence of fetal tissue. Complete moles usually (75–80%) arise as a consequence of duplication of a single sperm following fertilisation of an ‘empty’ ovum. Some complete moles (20–25%) can arise after disper...

BACKGROUND AND OBJECTIVES Human chorionic gonadotropin (HCG) and thyrotrophic hormone (TSH) have analogies in their structures, as well as in their receptors. The high levels of HCG seen in gestational trophoblastic diseases may induce secondary hyperthyroidism. The objective of this report was to present a case in which the administration of iodinated contrast triggered a thyrotoxic crisis. ...

Placental site trophoblastic tumour (PSTT) is a rare form of trophoblastic disease accounting for < 2% of all gestational trophoblastic neoplasms. Most of the cases follow a normal pregnancy and a small number have a preceeding molar pregnancy or spontaneous abortion. It can occur as early as several weeks or as late as 15 years after normal delivery, molar pregnancy or abortion. Excessive inte...

Gestational trophoblastic diseases are a heterogenous group of conditions ranging from the benign hydatidiform mole to the malignant choriocarcinoma. Optimal therapy in this group of diseases rest in the correct diagnosis, assessing their risk for malignant behavior using prognostic scoring systems and administering appropriate treatment. Their rarity makes it imperative that these patients are...