Interindividual variability in pain sensitivity and the response to analgesic manipulations remains a considerable clinical challenge as well as an area of intense scientific investigation. Techniques in this field have matured rapidly so that much relevant data have emerged only in the past few years. Our increasing understanding of the genetic mediation of these biological phenomena have none...

The past decade has seen a major shift in the genetic study of human intelligence; where classic studies aimed to quantify the heritability of intelligence, current studies aim to dissect this heritability into its molecular-genetic components. Five whole-genome linkage scans have been published in the past year, converging on several chromosomal (or genomic) regions important to intelligence. ...

The State of Rio Grande do Sul (RS) is the largest producer of oat in Brazil with the aid of consolidated breeding programs, which are constantly releasing new cultivars. The main objectives of this study were to: 1) evaluate the annual genetic progress in grain yield and hectoliter weight of the oat cultivars in RS, with and without fungicide use on aerial parts of plants; and 2) evaluate the ...

A recent study in BMC Evolutionary Biology has shown that genetically similar individual ring-tailed lemurs are also more similar in their scent composition, suggesting a possible mechanism of kin recognition. Theoretical and experimental studies reveal challenges ahead in achieving a true systems-level understanding of this process and its outcomes.

pISSN: 2093-940X, eISSN: 2233-4718 Copyright c 2015 by The Korean College of Rheumatology. All rights reserved. This is a Free Access article, which permits unrestricted non-commerical use, distribution, and reproduction in any medium, provided the original work is properly cited. Review Article Journal of Rheumatic Diseases Vol. 22, No. 5, October, 2015 http://dx.doi.org/10.4078/jrd.2015.22.5.274

the rapid progress of science and technology, including genetic research and technology has been led to new hopes in the treatment of some genetic conditions and diseases. but these developments have also raised ethical and societal concerns in different communities. certainly, medical genetics knowledge should be applied so, we have to maximize its benefits and minimize any harm. in recent dec...

Ants are among the most remarkable and successful of animal taxa. The success of ants stems from their complex social systems, which originate, in part, from the genetic composition of individual society members. In this review, we evaluate progress in understanding how genetic information influences complex phenotypes in ants. We find that research on the structure of ant genomes has been stro...

aBstract Intelligence is a highly heritable complex trait. The proportion of variance in intelligence that is attributable to genetic factors ranges from 40% in young childhood to 80% in late adulthood. In the past decade, considerable progress has been made in molecular genetics technologies, which facilitates the detection of the actual genetic factors that underlie the high heritability of i...

Brain structure and function are determined in part through experience and in part through our inherited genes. A powerful approach for unravelling the balance between activity-dependent neuronal plasticity and genetic programs is to directly manipulate the genome. Such molecular genetic studies have been greatly aided by the remarkable progress of large-scale genome sequencing efforts. Sophist...