a case with two simultaneous dens invaginations (dis) and one dens evagination (de) in a permanent maxillary lateral incisor is reported for the first time in a 21-year-old girl. de known as talon cusp of the anterior teeth is a rare entity and its co-existence with di has been reported scarcely in the literature. simultaneous occurrence of two dis with one de has not been reported elsewhere. u...

Background/Aim: Recurrent pregnancy loss (RPL), described as the of two or more pregnancies before 24 weeks pregnancy, remains a concern for both couples and clinicians. Genetic factors tend to be strongly linked reproductive failure among different etiologies. Our goal was determine rates kinds chromosomal defects in who had repeated losses history miscarriage first trimester. Methods: This cr...

Relevance: Breast cancer (BC) is the leading cause of worldwide female mortality. The constant development treatment
 strategies and diagnostic tools has increased survival rate for BC. Next-generation genome sequencing (NGS) identifies genetic
 changes responsible tumor emergence, development, metastasis. NGS expanded capacities BC diagnostics, treatment,
 early prevention in wo...

It is known that perinatal mortality is caused in 20-25 percent of cases by inhaerited anomalies of fetuses and many of theese might be explained by genetic disorders. In general genetic disorder is a condition caused by abnormalities in genes or chromosomes. Chromosomes are complex bodies in cell nucleus as carriers of genes. While some diseases are due to genetic abnormalities acquired in a f...

A large number of human diseases arise as a result of genetic abnormalities. With the advent of improved molecular biology techniques, the genetic etiology of male infertility is increasing. The common genetic factors responsible for male infertility are chromosomal abnormalities, Yq microdeletion and cystic fibrosis. These are responsible for approximately 30 percent cases of male infertility....

introduction: infertility is a significant multifactorial disorder that can be caused by chromosomal abnormalities. in this study, we aimed to cytogenetically investigate male and female patients admitted to the genetic diagnostic laboratory of kayseri educational hospital in kayseri, turkey with varied clinical prediagnoses of infertility. materials and methods: chromosomes from cultured perip...

background: the sperm count and function may be affected by karyotype abnormalities or microdeletion in y chromosome. these genetic abnormalities can probably transmit to the children. objective: in this study, we tried to determine the frequency of karyotype abnormalities and y chromosome microdeletions in severe oligospermic or azoospermic men who fathered sons by icsi. materials and methods:...

The difficulty in predicting early cancer is due to the lack of illness indicators. Metaheuristic approaches are a family algorithms that seek find optimal values for uncertain problems with several implications optimization and classification problems. An automated system recognizing illnesses can respond accuracy, efficiency, speed, helping medical professionals spot abnormalities lowering de...

Chromosome anomalies belong to genetic factors, which participate on etiology of reproductive failure. The aim of the study was to investigate the frequency of chromosome abnormalities in infertile men in the Prešov region in Slovakia (1998-2014). Karyotyping using G-banding and C-banding methods was performed in 1426 subjects including 948 infertile men and 478 controls. Karyotype analyses rev...