نتایج جستجو برای: gene optimization
تعداد نتایج: 1450764 فیلتر نتایج به سال:
Lipases catalyze hydrolysis and synthesis of triacylglycerols. These enzymes,especially the microbial ones, have wide commercial and industrial usage. Bacillus subtilis <span style="color: ...
Introduction Phytase is an enzyme that has the ability to break down phytic acid into myoinositol and mineral phosphate, and widely uses as an additive in animal foods. The aim of this study was to achieve a high level of bacterial phytase expression in PET26b expression host. Materials and Methods To generate the recombinant phytase enzyme, the target gene was introduced into the expression ...
in this paper, we study the problem of minimizing the ratio of two quadratic functions subject to a quadratic constraint. first we introduce a parametric equivalent of the problem. then a bisection and a generalized newton-based method algorithms are presented to solve it. in order to solve the quadratically constrained quadratic minimization problem within both algorithms, a semidefinite optim...
Abstract Background and purpose: Delayed wound healing is a common complication of diabetes mellitus. However, less is known about the cause of this pathology. Types of skin cells, extracellular matrix and variety of growth factors are involved in wound healing. The use of recombinant growth factors in researches and production of skin substitutes are still a challenge. Much research has bee...
Abstract Introduction: Genetic variation of FGFR3 gene is one of the factors affecting the bladder tumor. FGFR3 is a tyrosine kinase receptor, involved in controlling the cellular and angiogenesis cycle. This protein affects a variety of diseases and cancers and cartilage growth abnormalities. Regarding the high activity of fgfr3 mutations in more than 50% of primary tumors of bladder urethral...
Introduction & Objective: Interleukine-1 receptor antagonist (IL-1RA) is a powerful anti-inflammatory cytokine which limits the biological effects of IL-1. Due to structural similarity between IL-1 and its antagonist, IL-1RA competitively binds to IL-1 receptor which leads to no signal transduction. Therefore , it is applied in the treatment of patients with inflammatory diseases such as Rheu...
Fermentation technology has a long history and low-temperature fermentation now become the focus of research. This paper reviews mechanism application optimization relevant strains. Low-temperature leads to differential expression growth in metabolism genes (PSD1, OPI3, ERG3, LCB3 NTH1). can be applied foods various advantages, such as increasing changes volatile flavor compounds other correspo...
In the area of bioinformatics, the identification of gene subsets responsible for classifying available disease samples to two or more of its variants is an important task. Such problems have been solved in the past by means of unsupervised learning methods (hierarchical clustering, self-organizing maps, k-mean clustering, etc.) and supervised learning methods (weighted voting approach, k-neare...
many factors including genetic, environmental, and acquired are involved in breast cancer development across various societies. among all of these factors in families with a history of breast cancer throughout several generations, genetics, like predisposing genes to develop this disease, should be considered more. early detection of mutation carriers in these genes, in turn, can play an import...
in recent years, due to absence of integrated watershed management in most regions, natural resources have witnessed numerous damages with severe floods as one of its consequences which further leads to economic, social and environmental damages. presently, there is no optimal utilization of land in most watersheds hence no optimal model matching with facilities and objectives is used in the wa...
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