PURPOSE Physiologic gaze-evoked nystagmus (GEN) is one of many normal eye movements seen on the neurologic examination. GEN occurring at gaze angles >45 degrees is considered a positive sign in the Horizontal Gaze Nystagmus Test (HGNT) used by United States police officers to determine alcohol intoxication. METHODS The authors enrolled 56 subjects after a brief survey and a neurologic examina...

We cloned the rpoN (ntrA, glnF) gene encoding the alternate sigma factor sigma(54) from the opportunistic multihost pathogen Pseudomonas aeruginosa strain PA14. A marker exchange protocol was used to construct the PA14 rpoN insertional mutation rpoN::Gen(r). PA14 rpoN::Gen(r) synthesized reduced levels of pyocyanin and displayed a variety of phenotypes typical of rpoN mutants, including a lack ...

BACKGROUND Despite optimal primary treatment of ovarian cancer, overall prognosis is poor due to recurrences. While steroid hormone receptors are frequently expressed, the role of estrogen receptor (ER) in ovarian carcinogenesis, response to treatment or prognosis has not been established. We analyzed the gene-expression in response to estradiol (E2) and genistein (Gen) in ovarian cancer cells....

The taxonomic position of two antarctic dorylaimid species Amblydorylaimusisokaryon (Loof, 1975) Andrássy, 1998 and Pararhyssocolpusparadoxus (Loof, 1975), gen. n., comb. n. are discussed on the basis of morphological, including SEM study, morphometric, postembryonic and sequence data of 18S rDNA and the D2-D3 expansion fragments of large subunit rDNA. The evolutionary trees inferred from 18S s...

One new genus and two new species of the family Desmodoridae are described from the upper continental slope of New Zealand, at 350-1240 m water depths. Onepunema gen. n. is characterised by a striated head capsule, small buccal cavity without teeth, and presence of two testes. Onepunema gen. n. can be differentiated from all other genera of the family by the presence of two testes, which is an ...

The computational discovery of DNA motifs for previously uncharacterized transcription factors in groups of co-regulated genes is a well-studied problem with a great deal of practical relevance to the biologist. In this paper, we applied an improved hybridization of adaptive Biogeography-Based Optimization (ABBO) with differential evolution (DE) approach, namely ABBO/DE/GEN, to predict motifs f...

Devising an optimal strategy for navigation in a partially observable environment is one of the key objectives in AI. One of the problem in this context is the Canadian Traveler Problem (CTP). CTP is a navigation problem where an agent is tasked to travel from source to target in a partially observable weighted graph, whose edge might be blocked with a certain probability and observing such blo...

BACKGROUND This study aimed to find the strength of the correlation between ORange(®) (intraoperative wavefront aberrometer) objective refraction during pseudophakic cataract surgery (Gen 1) and 1-week objective autorefraction postcataract surgery in order to establish the clinical degree of confidence in the ORange. Gen 1 was used because Gen 2 was not available at the time of the study. Howev...

The red algal order Bangiales has been revised as a result of detailed regional studies and the development of expert local knowledge of Bangiales floras, followed by collaborative global analyses based on wide taxon sampling and molecular analyses. Combined analyses of the nuclear SSU rRNA gene and the plastid RUBISCO LSU (rbcL) gene for 157 Bangiales taxa have been conducted. Fifteen genera o...