New regulations in the United States and Europe, designed to address climate change concerns by reducing greenhouse gas emissions, are causing increased use of gasoline direct-injection (GDI) engines in light-duty vehicles (LDV). Separate new regulations that aim to reduce particulate emissions to address air pollution concerns are taking effect concurrent with greenhouse gas limitations in bot...

STIMULUS-SECRETION COUPLING of insulin is a highly orchestrated process initiated by the uptake of glucose by pancreatic -cells culminating with the fusion of insulin vesicles with the plasma membrane and release of insulin into the extracellular space. A hallmark feature of stimulus-secretion coupling is the biphasic nature of insulin secretion following an elevation in plasma glucose levels (...

PURPOSE The purpose of our study was to investigate the effect of gait training with rhythmic auditory stimulation (RAS) on both kinematic and temporospatial gait patterns in patients with hemiplegia. MATERIALS AND METHODS Eighteen hemiplegic patients diagnosed with either cerebral palsy or stroke participated in this study. All participants underwent the 4-week gait training with RAS. The tr...

Regulation of ionic channels plays a pivotal role in controlling cardiac function. Here we show that the Rho family of small G proteins regulates L-type Ca2+ currents in ventricular cardiomyocytes. Ventricular myocytes isolated from transgenic (TG) mice that overexpress the specific GDP dissociation inhibitor Rho GDI-alpha exhibited significantly decreased basal L-type Ca2+ current density (app...

Objective: The goal of this study was to utilize Gait Profile Score (GPS) and Deviation Index (GDI), assess its capability differentiating between injured non-injured runners. Design: In total, 45 long-distance runners (15 non-injured, 30 injured), diagnosed with one the following running related injuries, patella femoral pain syndrome, iliotibial medial tibial stress were recruited. Methods: D...

The climate change issue has become a growing concern due to the increasing greenhouse gas emissions. To achieve carbon neutrality for mitigating problem, oxy-fuel combustion (OFC) technique on internal engines (ICEs) attracted much attention. Furthermore, water injection (WI) strategy was proven effective in improving process and thermal efficiency under OFC mode. However, WI effects gasoline ...

Barely visible impact damage (BVID) on carbon fibre reinforced polymer (CFRP) aerospace components can create interlaminar defects that may deteriorate during operation with potential failure as a result. Especially damage-prone regions such the feet of stiffener must therefore be inspected for BVIDs frequently, which is an effort increases downtimes and operational costs. The optical sensors p...

With the introduction of gasoline particulate filters (GPFs), particle number (PN) emissions direct-injection (GDI) vehicles are below European regulatory limit 6 × 1011 p/km under certification conditions. Nevertheless, concerns have been raised regarding emission levels at boundaries ambient and driving conditions real-driving (RDE) regulation. A Euro 6d-Temp GDI vehicle with a GPF was tested...