TO THE EDITOR: In a recent article (1), my friend and colleague Grant Gullberg presented a method for the calculation of ejection fraction in gated myocardial perfusion SPECT studies. The crucial point is the avoidance of edge detection. In their method, the authors used the maximal activity plane as the ventricular delineator. The originality of the method resides in the latter, not in the for...

Purpose: Regadenoson (REG) is currently becoming the stress agent of choice in patients undergoing pharmacologic single photon emission computed tomography (SPECT). However, in patients with left bundle branch block (LBBB) and ventricular paced rhythm (VPR), hesitation exists amongst clinicians to use REG-SPECT due to the concern that the increased heart rate could cause false positive SPECT re...

We evaluated whether BNP has additive value to SPECT in patients with normal left ventricular (LV) systolic function. Data from 224 consecutive patients who underwent rest (201)Tl-dipyridamole stress (99m)Tc-sestamibi gated SPECT and coronary angiography due to chest pain were analyzed. Patients with true positive SPECT showed significant higher BNP level than those with false positive defect (...

We present the case of a 65-year-old man with dyspnea and chest discomfort referred for dipyridamole myocardial perfusion scintigraphy. 99mTc-sestamibi cardiac gated SPECT images showed an irreversible hypoperfusion in the mid-ventricular portion of anteroseptal wall, a suspicious reversible hypoperfusion in the apical slices of inferolateral wall, and left ventricle dilatation with a ejection ...

Background FFR was initially validated against SPECT, Dobutamine Stress Echo and Exercise Testing [1]. It is now frequently used to determine the management of intermediate coronary artery stenosis. A cut-off value of 0.75 is used in clinical practice to guide revascularisation supported by long-term outcome data [2], but a ‘grey zone’ of 0.75-0.8 with uncertain clinical significance exists [3]...

Electrocardiographic gating is increasingly used for 82Rb cardiac PET/CT, but reference ranges for global functional parameters are not well defined. We sought to establish reference values for left ventricular ejection fraction (LVEF), end systolic volume (ESV), and end diastolic volume (EDV) using 4 different commercial software packages. Additionally, we compared 2 different approaches for t...