The objective was to investigate whether transgastric Natural Orifice Transluminal Endoscopic Surgery (NOTES) could be implemented safely in clinical practice. The experimental studies proved ultrasonography guided access through the stomach to be feasible and safe without iatrogenic complications. Although the technique was safe, further development is needed to increase reproducibility and re...

The management of carcinoma of the oesophagus poses formidable logistic problems in countries such as Transkei where the condition is common and resources are limited. Most patients present late, often with complications, and are reluctant to undergo major surgery. Two hundred and fifty consecutive patients who presented over nine months in Transkei were studied. The incidence increased with ag...

BACKGROUND 'Mules' or body packers are people who transport illegal drugs by packet ingestion into the gastrointestinal tract. These people are otherwise healthy and their management should maintain minimal morbidity. In this study, experience with body packers is presented and an algorithm for conservative and surgical management is provided. METHODS The clinical patient database for all bod...

G m r m m i o T E D The ASGE Technology Committee provides reviews of new or emerging endoscopic technologies that have the potential to affect the practice of GI endoscopy. Evidencebased methodology is used, with a MEDLINE literature search to identify pertinent preclinical and clinical studies on the topic and a MAUDE (U.S. Food and Drug Administration Center for Devices and Radiological Heal...

To cite: Meshikhes A-WN, Al-Dolah Q. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013201296 DESCRIPTION A 35-year-old mentally retarded man was admitted with a 3-day history of epigastric pain, vomiting and feeling of fullness. Clinically, he was pale, but was not in distress and his vital signs were normal. Abdominal examination revealed deep tenderness and a...

Abstract Introduction: taVNS improves oral feeding in newborns who are failing feeds but is ineffective Infants of Diabetic Mothers (IDM) with lower CNS glutathione(GSH) concentrations a prior trial. We hypothesized that mitigating oxidative stress N-acetylcysteine(NAC) to would enhance motor learning IDM and achieve full feeds. measured PK GSH changes NAC. Methods: Following informed consent, ...

A 58-year-old lady presented with persistent dysphasia, more for solids than liquids, associated with vomiting and loss of appetite since 1 month. She gave a history of insertion of Mosseau-barbin (MB) tube for chronic dysphasia 15 years ago. Barium swallow demonstrated an oesophageal stent insitu along with dilatation of the lower end of the oesophagus with stagnation of contrast and “bird-bea...

PURPOSE To analyze mucosal proliferation and its characteristics, through specific models of duodenogastric reflux, in the stomach of Wistar rats. METHODS Seventy-five healthy and adult male rats were divided into three groups: group I--control (n = 25 animals), submitted to gastrotomy of the posterior wall of the glandular stomach; group II--DGR (n = 25 animals), submitted to duodenogastric ...