Objectives: There are various obstacles in the eradication of Helicobacter.pylori (H. pylori) infections, including low antibiotic levels and poor accessibility of the drug at the site of the infection. This study describes the preparation and characterisation of novel floatingmucoadhesive alginate beads loaded with clarithromycin (CMN) for delivery to the gastric mucosa to improve the eradicat...

nanotechnology is the study of manipulating matter on an atomic and molecular scale. generally, nanotechnology deals with developing materials, devices, or other structures possessing at least one dimension size from 1 to 100 nanometers .  carbon nanotubes have great potentials for novel applications in industry, drug delivery system and many other uses. in this work after purification, multiwa...

The gastroretentive dosage forms have potential for use as controlled-release drug delivery systems. The use of floating dosage forms is one method to achieve prolonged gastric residence times, providing opportunity for both local and systemic drug action. The present investigation involve the development and in vitro evaluation of the floating matrix tablets, which after oral administration ca...

a great challenge in using natural polysaccharide as drug delivery system is their fast drug release. the purpose of the present study was to prepare and evaluate chitosan oligosaccharide (cho)-de-estrifiedtragacanth (det) core-shell nanoparticles for controled release of water soluble drugs. cho-det nanoparticles were prepared by microemulsion method and characterized by ft-ir spectroscopy. si...