The patient, a 40-year-old male, was referred to our clinic with intermittent nausea, vomiting and symptomatic anemia for 4 months. Notable hematological indices were low hemoglobin levels of 9.6 g/dl and hematocrit levels of 35.8%, while after receiving two units of concentrated red blood cells, at discharge; they achieved levels of 15.2 g/dl and 42.3%, respectively. Esophagogastroduodenoscopy...

Bile reflux gastritis is due to an excessive reflux of duodenal contents into the stomach. The increased enterogastric reflux may provide the basis for increased mucosal injury. Bile reflux gastritis can appear in two circumstances: gastric resection with ablation of pylorus and primary biliary reflux due to the failure of pylorus. The aim of the study was to evaluate the endoscopical and histo...

BACKGROUND/AIMS Elevated levels of serum gastrin (SG) have been associated with tumorigenic effects in a number of gastrointestinal cancers. We decided to investigate the relationship between SG and gastric epithelial lesions. MATERIALS AND METHODS A total of 90 patients with gastric epithelial lesions (hyperplastic polyp, 12; adenoma, 41; early gastric cancer, 29; advanced gastric cancer, 8)...

CONTEXT Gastric adenoma is a precursor lesion of the adenocarcinoma. OBJECTIVE To characterize gastric adenomas according to the mucin immunoexpression and to evaluate the immunoexpression of p53, p16ink4a, BCL-2, cyclin D, Ki-67, in the adenoma and in the gastric mucosa harboring adenoma. METHODS Forty gastric specimens from 20 patients were classified as intestinal (MUC2-goblet cell mucin...

Goal. Surgeons that remove a typical polyp from the stomach or small intestine should be reluctant to accept a diagnosis of GIST just because there is a mutation in platelet-derived growth factor receptor alfa (PDGFRA). Background. A subtype of gastric and intestinal polyps is denoted as inflammatory fibroid polyp (IFP). In some of these cases a mutation in PDGFRA is found, leading to the diagn...

Address correspondence to: Dr. Chintan Modi, Saint Michael’s Medical Center, 111 Central Avenue, Newark, NJ 07102; Tel: 973-877-5351; Fax: 973-877-2984; E-mail: [email protected] The inflammatory fibroid polyp (IFP) is an uncommon benign tumor of the gastrointestinal tract. The tumor was first described in 1949 by Vanek as a gastric submucosal granuloma with eosinophilia.1,2 It has also been...

BACKGROUND Gastric cancer is one of the most frequent malignancies in the world, ranking fifth in the Netherlands as a cause of cancer death. Surgery is the only curative treatment for advanced cases, but results of gastrectomy largely depend on the stage of the disease. A better understanding of the mechanisms of progression from a preneoplastic condition through intraepithelial neoplasia to i...

Hyperplastic polyps are lesions that are mostly smaller than 1 cm; they are sessile and innocuous. They develop as a result of tissue damage and an exaggerated mucosal regeneration. Intestinal metaplasia and dysplasia at a rate of 1–20% may be seen in hyperplastic polyps. However, the risk of carcinoma development is less than 2%. The risk increases in multiple polyps (1). Here we present a cas...

87 Summary Bleeding, including gastrointestinal bleeding, is one of the most frequently encountered problems in surgical practice. The spectrum of causes comprises also an uncommon gastrointestinal pathology – inflammatory fibroid polyp. In order to diagnose the disease correctly and to choose the appropriate treatment, greater awareness of this rare entity is necessary.