Morphological evidence of apoptosis in transient forebrain ischemia is controversial. We therefore investigated the time sequence of apoptosis-related antigens by immunohistochemistry and correlated it with emerging nuclear patterns of cell death in a model of transient forebrain ischemia in CA1 pyramidal cells of the rat hippocampus. The earliest ischemic changes were found on day 2 and 3, ref...

The objective of this report is to prove that even after development of ischemic necrosis of the muscles and nerves, we can still save the extremity or the knee and even several days after arterial injury, perform arterial repair and other mentioned procedures. Thus we can retain a functionally satisfactory leg or knee joint, which is far better than classic above-knee amputation and utili...

1 of 5 BACKGROUND Cases of gastric ischaemia are very rare but are important to consider as they are associated with a high mortality following surgical resection of necrotic tissue. A number of cases have been described relating to a number of causes ranging from ingestion of caustic substances to extreme acute gastric dilatation. We present an unusual presentation of concurrent small bowel pe...

Introduction. The spectrum of gastric injury due to corrosives can vary. This paper presents a single center experience of over 30 years of corrosive gastric injuries of 39 patients with acute gastric injuries from 1977 till 2006. Patients and Methods. Two thirds of the patients in the acute injury group had a concomitant esophageal injury. The age of the patients ranged from 4 years to 65 year...

Individuals with Prader-Willi syndrome (PWS) have excessive appetite with the ability to consume large quantities of food. Absence of vomiting and a high pain threshold are considered manifestations of the disorder. We present 6 patients with PWS with acute dramatic gastric distention. In 3 young adult women with vomiting and apparent gastroenteritis, clinical course progressed rapidly to massi...

Select group of patients with concurrent esophageal and gastric stricturing secondary to corrosive intake requires colonic or free jejunal transfer. These technically demanding reconstructions are associated with significant complications and have up to 18% ischemic conduit necrosis. Following corrosive intake, up to 30% of such patients have stricturing at the pyloro-duodenal canal area only a...