This study proposes and simulates an inverse treatment planning and a continuous dose delivery approach for the Leksell Gamma Knife (LGK, Elekta, Stockholm, Sweden) which we refer to as "Tomosurgery." Tomosurgery uses an isocenter that moves within the irradiation field to continuously deliver the prescribed radiation dose in a raster-scanning format, slice by slice, within an intracranial lesi...

AIM Effectiveness and safety of gamma knife radiosurgery (GKRS) for hemorrhagic brainstem cavernous malformations (BSCM) is still an unresolved problem. The purpose of this study was to assess treatment results of GKRS for hemorrhagic BSCMs. MATERIAL AND METHODS A retrospective review was performed of patients with hemorrhagic BSCMs who were treated at the Acıbadem Kozyatağı Hospital GKRS uni...

The role of radiosurgery for cavernous malformations of the brain remains to be fully defined. We have used Gamma Knife radiosurgery for selected patients with symptomatic, hemorrhagic malformations in high-risk brain locations. Indications, techniques, and results are presented.

Brain Metastasis (BM) is the most common type of intracranial malignancies in adult. Lung, breast cancer and melanoma are the malignancies which contribute up to 80% of BM [1]. Until recently, the median overall survival for patients with BM has been troubled, and in general the expected survival is at most 6 months after diagnosis [2]. However, owing to the advance of sensitive imaging modalit...

BACKGROUND Gamma Knife (GK) surgery is a recognized treatment option for the management of small to medium-sized vestibular schwannoma (VS) associated with high-tumor control and low morbidity. When a radiosurgical treatment fails to stop tumor growth, repeat GK surgery can be proposed in selected cases. METHODS A series of 27 GK retreatments was performed in 25 patients with VS; 2 patients u...

The long-term outcome of gamma knife radiosurgery (GKS) for central neurocytomas remains unclear. In the present study, we retrospectively reviewed the medical records of 7 patients with 8 central neurocytomas who underwent GKS between March 1997 and April 2007. They were 3 men and 4 women age ranging 9 to 53 years old (mean 32.5 years old). The tumor volume at the time of GKS was 0.34-6.10 cm(...

Microsurgical resection, stereotactic radiosurgery (SRS), and conservative management are three methods of treatment for intracranial cavernomas. However if left untreated, cavernomas may lead to intracerebral hemorrhage, seizures, focal neurologic deficits, or headaches. Deciding how to manage a cavernoma patient depends on a multitude factors. While microsurgery is the standard treatment for ...

The management of brainstem metastases is challenging. Surgical treatment is usually not an option, and chemotherapy is of limited utility. Stereotactic radiosurgery has emerged as a promising palliative treatment modality in these cases. The goal of this study is to assess our single institution experience treating brainstem metastases with Gamma Knife radiosurgery (GKRS). This retrospective c...

Radiosurgery is a surgical procedure associated with minimal functional morbidity and allows patients to return rapidly to their previous level of activity. Most tumors regress in volume with extended follow-up, and the rare occurrence of tumor growth after radiosurgery seems to occur early. Similarly, cranial neuropathy or other neurologic symptoms after irradiation occur within the first few ...